Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation. - Wikidata - awgldk - TriplyDB

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

http://www.wikidata.org/entity/Q33697682

about

Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression The RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cells RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients.Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information Gene expression profile and functionality of ESC-derived Lin-ckit+Sca-1+ cells are distinct from Lin-ckit+Sca-1+ cells isolated from fetal liver or bone marrow Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the making Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation Unraveling the molecular pathophysiology of myelodysplastic syndromes.Identifying Nuclear Matrix-Attached DNA Across the Genome.Mouse models for core binding factor leukemia.Runx1 Structure and Function in Blood Cell Development.Acute myeloid leukemia with the t(8;21) translocation: clinical consequences and biological implications.

P2860

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P2860

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

http://www.wikidata.org/entity/Q33697682

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Definitive hematopoiesis requi ...... targeting and transactivation.

@ast

Definitive hematopoiesis requi ...... targeting and transactivation.

@en

type

label

Definitive hematopoiesis requi ...... targeting and transactivation.

@ast

Definitive hematopoiesis requi ...... targeting and transactivation.

@en

prefLabel

Definitive hematopoiesis requi ...... targeting and transactivation.

@ast

Definitive hematopoiesis requi ...... targeting and transactivation.

@en

P1433

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P1433

Human Molecular Genetics

P1476

Definitive hematopoiesis requi ...... targeting and transactivation

@en

P2093

Andre J van Wijnen

http://www.w3.org/2001/XMLSchema#string

Christopher R Dowdy

http://www.w3.org/2001/XMLSchema#string

Dana Frederick

http://www.w3.org/2001/XMLSchema#string

Diana Vradii

http://www.w3.org/2001/XMLSchema#string

Gary S Stein

http://www.w3.org/2001/XMLSchema#string

Jane B Lian

http://www.w3.org/2001/XMLSchema#string

Janet L Stein

http://www.w3.org/2001/XMLSchema#string

Ronglin Xie

http://www.w3.org/2001/XMLSchema#string

Sadiq Hussain

http://www.w3.org/2001/XMLSchema#string

Stephen N Jones

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis.

Possible involvement of RasGRP4 in leukemogenesis.

P304

1048-1057

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P31

scholarly article

P356

10.1093/HMG/DDP568

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P433

6

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P478

19

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P50

Sayyed K. Zaidi

P577

2009-12-24T00:00:00Z

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P5875

40774153

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P698

20035012

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P921

P932

2830828

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