A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C.

A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C.

Item
http://www.wikidata.org/entity/Q33698314
A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARXX chromosome regulation: diverse patterns in development, tissues and disease.Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin.Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C.Epigenetic programming of hypoxic-ischemic encephalopathy in response to fetal hypoxia.Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity.Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.Histone lysine demethylases as targets for anticancer therapy.Jumonji family histone demethylases in neural development.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.New Insights Into Intellectual Disability Caused by Mutations in a Chromatin Regulator.Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets.JARID1 Histone Demethylases: Emerging Targets in Cancer.Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C.A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5.The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila.
P2860

A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C.

Item
http://www.wikidata.org/entity/Q33698314
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A distinctive gene expression ...... the histone demethylase KDM5C.
@ast
A distinctive gene expression ...... the histone demethylase KDM5C.
@en
type
label
A distinctive gene expression ...... the histone demethylase KDM5C.
@ast
A distinctive gene expression ...... the histone demethylase KDM5C.
@en
prefLabel
A distinctive gene expression ...... the histone demethylase KDM5C.
@ast
A distinctive gene expression ...... the histone demethylase KDM5C.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P6179
P698
P932
P356
P1433
P1476
A distinctive gene expression ...... the histone demethylase KDM5C.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P6179
P698
P932