An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.
about
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesisImproved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2.An Ad5[E1-, E2b-]-HER2/neu vector induces immune responses and inhibits HER2/neu expressing tumor progression in Ad5 immune mice.Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.Phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibition [corrected].Increasing vaccine potency through exosome antigen targeting.Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells.Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment.Polyclonal immune responses to antigens associated with cancer signaling pathways and new strategies to enhance cancer vaccinesViral gene therapy for breast cancer: progress and challenges.An Adenoviral Vector Encoding Full-Length Dectin-1 Promotes Aspergillus-Induced Innate Immune Response in Macrophages.Concurrent HER2 vaccination and inhibition of kinase activity: safety and immunogenicity.Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers
P2860
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P2860
An adenoviral vaccine encoding full-length inactivated human Her2 exhibits potent immunogenicty and enhanced therapeutic efficacy without oncogenicity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@ast
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@en
type
label
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@ast
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@en
prefLabel
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@ast
An adenoviral vaccine encoding ...... efficacy without oncogenicity.
@en
P2093
P2860
P1476
An adenoviral vaccine encoding ...... efficacy without oncogenicity
@en
P2093
Amy Hobeika
Andrea Amalfitano
Dong-Wan Kim
Gangjun Lei
Gayathri Devi
Jeffrey Marks
Junping Wei
Michael A Morse
Neil Spector
Oliver Glass
P2860
P304
P356
10.1158/1078-0432.CCR-09-2549
P407
P577
2010-02-23T00:00:00Z