Rational assignment of key motifs for function guides in silico enzyme identification.
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Microbial enzymes: tools for biotechnological processesHydroxynitrile Lyases with α/β-Hydrolase Fold: Two Enzymes with Almost Identical 3D Structures but Opposite Enantioselectivities and Different Reaction MechanismsBiochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxusPhosphodeoxyribosyltransferases, Designed Enzymes for Deoxyribonucleotides SynthesisCrystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLPStructural studies ofPseudomonasandChromobacteriumω-aminotransferases provide insights into their differing substrate specificityCrystal Structure of an (R)-Selective ω-Transaminase from Aspergillus terreusThe substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase fromNectria haematococcaCrystal structure determination and mutagenesis analysis of the ene reductase NCRCrystallographic characterization of the (R)-selective amine transaminase from Aspergillus fumigatusStructural and biochemical characterization of the dual substrate recognition of the (R)-selective amine transaminase from Aspergillus fumigatusFirst structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-aminesRevisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis.Engineering of biocatalysts - from evolution to creation.Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.Continuous colorimetric screening assays for the detection of specific L- or D-α-amino acid transaminases in enzyme libraries.Novel thermostable amine transferases from hot spring metagenomes.Development of novel sugar isomerases by optimization of active sites in phosphosugar isomerases for monosaccharides.Constructing de novo biosynthetic pathways for chemical synthesis inside living cells.Discovery and structural characterisation of new fold type IV-transaminases exemplify the diversity of this enzyme foldFeatures and technical applications of ω-transaminases.Protein design in systems metabolic engineering for industrial strain development.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.The Industrial Age of Biocatalytic Transamination.Modern Approaches to Discovering New Hydroxynitrile Lyases for Biocatalysis.GH13 amylosucrases and GH70 branching sucrases, atypical enzymes in their respective families.Bacillus anthracis ω-amino acid:pyruvate transaminase employs a different mechanism for dual substrate recognition than other amine transaminases.Bioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases.In Silico Identification for α-Amino-ε-Caprolactam Racemases by Using Information on the Structure and Function Relationship.Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds.An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic IminesControlling stereoselectivity by enzymatic and chemical means to access enantiomerically pure (1S,3R)-1-benzyl-2,3-dimethyl-1,2,3,4-tetrahydroisoquinoline derivatives.A new target region for changing the substrate specificity of amine transaminasesA novel transaminase, (R)-amine:pyruvate aminotransferase, from Arthrobacter sp. KNK168 (FERM BP-5228): purification, characterization, and gene cloning.Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes.Crystallization and preliminary X-ray diffraction studies of the (R)-selective amine transaminase from Aspergillus fumigatus.Concise Chemoenzymatic Three Step Total Synthesis of Isosolenopsin Through Medium Engineering.Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts.Expanding dynamic kinetic protocols: transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives.Active site model of (R)-selective ω-transaminase and its application to the production of D-amino acids.
P2860
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P2860
Rational assignment of key motifs for function guides in silico enzyme identification.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rational assignment of key motifs for function guides in silico enzyme identification.
@ast
Rational assignment of key motifs for function guides in silico enzyme identification.
@en
type
label
Rational assignment of key motifs for function guides in silico enzyme identification.
@ast
Rational assignment of key motifs for function guides in silico enzyme identification.
@en
prefLabel
Rational assignment of key motifs for function guides in silico enzyme identification.
@ast
Rational assignment of key motifs for function guides in silico enzyme identification.
@en
P2093
P356
P1476
Rational assignment of key motifs for function guides in silico enzyme identification.
@en
P2093
Helge Jochens
Karen Robins
Sebastian Schätzle
P2888
P304
P356
10.1038/NCHEMBIO.447
P577
2010-09-26T00:00:00Z