Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
about
Non-Coding RNAs Regulating Morphine Function: With Emphasis on the In vivo and In vitro Functions of miR-190Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system.Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization.Activation of protein kinase C (PKC)α or PKCε as an approach to increase morphine tolerance in respiratory depression and lethal overdoseIdentification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptorOpioid receptor desensitization: mechanisms and its link to toleranceModulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability.Morphine induces AMPA receptor internalization in primary hippocampal neurons via calcineurin-dependent dephosphorylation of GluR1 subunits.Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection.Posttranslation modification of G protein-coupled receptor in relationship to biased agonism.FK506-binding protein 12 modulates μ-opioid receptor phosphorylation and protein kinase C(ε)-dependent signaling by its direct interaction with the receptor.Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase CG protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?Epigenetics of µ-opioid receptors: intersection with HIV-1 infection of the central nervous system.The combined inhibitory effect of the adenosine A1 and cannabinoid CB1 receptors on cAMP accumulation in the hippocampus is additive and independent of A1 receptor desensitizationDeciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells.Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use.A continuous, fluorescence-based assay of μ-opioid receptor activation in AtT-20 cells.Effect of Tamoxifen and Brain-Penetrant Protein Kinase C and c-Jun N-Terminal Kinase Inhibitors on Tolerance to Opioid-Induced Respiratory Depression in Mice.Spinal or supraspinal phosphorylation deficiency at the MOR C-terminus does not affect morphine tolerance in vivo.Cellular tolerance at the µ-opioid receptor is phosphorylation dependent.
P2860
Q21131252-863A6EF6-2F40-4CCC-8595-CA7BADB45666Q21132308-94CAA383-0DB1-4091-873B-356EC1132D56Q33568279-448AAF7F-2915-40BE-B7C3-A031AC412E05Q34121723-74F31613-6CF8-4E5A-97ED-500B8A0CD6A9Q34482298-1D629E88-24F3-4DD3-BFC4-7425D61A86E4Q34729984-F2F141B0-7F29-4271-B32B-A7D3A3104DBEQ34752640-955761BC-E825-42BC-9902-98AD2820A3B5Q34776767-7E3E6906-1CF9-4A51-A421-E3479BF3D0B2Q35264421-83B1972D-8033-4E7B-BA8E-5934C69155E3Q36025329-106A249F-0288-4A5E-8B7A-FABFACFA4584Q36335620-453C0F28-9A80-4B0F-B42C-C3E303B166ECQ36591603-3D2CC44E-8D38-4AE2-AAA5-EFE215F3683CQ36763815-A2F37AAC-CEA0-4B5F-9017-0DA291902EF8Q37322612-2198CCA6-CD85-4B78-9EC4-B60B1C5BFD0AQ37405419-91A0B33A-25A3-43B0-B490-DE9852C59AA7Q37635282-A8DF6B9E-65CF-4E32-8629-8CCEF0774972Q37829756-7B65B105-5BD9-4144-AC52-CE41490CC890Q37950301-47FF50BC-AFD2-46BB-9C53-AD924140BBF0Q41820134-738442E2-F49F-4125-A3E2-A4C749A6FCC8Q42000724-AB109E90-8888-4485-AF88-CE9D8B181F3DQ42098623-7AEB282C-C977-47F4-8BD6-CC4D251CD277Q44336146-09644188-B344-4FAF-8B84-12A51C347F36Q44342944-CD1C2C4C-2B5E-498F-B050-A06FED85A723Q51145621-D420C5E4-6A33-44D2-BBA6-9A8C3A75611BQ54246867-78CEC343-4DD6-4F81-853E-71EC2D326F18
P2860
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@ast
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@en
type
label
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@ast
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@en
prefLabel
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@ast
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@en
P2093
P2860
P1433
P1476
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.
@en
P2093
P2860
P304
P356
10.1016/J.CELLSIG.2009.12.003
P577
2010-01-05T00:00:00Z