Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates. - Wikidata - awgldk - TriplyDB

Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.

Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.

http://www.wikidata.org/entity/Q33713108

about

Current prospects and challenges for epilepsy gene therapy Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound.Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain Gene therapy for metachromatic leukodystrophy.Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy.Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.Long-term channelrhodopsin-2 (ChR2) expression can induce abnormal axonal morphology and targeting in cerebral cortex Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Glial promoter selectivity following AAV-delivery to the immature brain.Comparative study of the transfection efficiency of commonly used viral vectors in rhesus monkey (Macaca mulatta) brains An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.Gene delivery with viral vectors for cerebrovascular diseases.Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction.Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice.Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype.Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.Gene-directed enzyme prodrug therapy for localized chemotherapeutics in allograft and xenograft tumor models.Gene therapy for the nervous system: challenges and new strategies.The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5.Fractalkine over expression suppresses α-synuclein-mediated neurodegeneration Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice.Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling.EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia.Direct and retrograde transduction of nigral neurons with AAV6, 8, and 9 and intraneuronal persistence of viral particles Widespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector.Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors.Strategies for targeting primate neural circuits with viral vectors.Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation.In vivo astrocytic Ca(2+) signaling in health and brain disorders.Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9.Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks.Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina Viral vectors for gene delivery to the central nervous system.Research advances in gene therapy approaches for the treatment of amyotrophic lateral sclerosis.Optogenetics in the nonhuman primate.

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Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.

http://www.wikidata.org/entity/Q33713108

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Efficient gene delivery and se ...... olated from nonhuman primates.

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Efficient gene delivery and se ...... olated from nonhuman primates.

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type

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Efficient gene delivery and se ...... olated from nonhuman primates.

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Efficient gene delivery and se ...... olated from nonhuman primates.

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Molecular Therapy

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Efficient gene delivery and se ...... solated from nonhuman primates

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Alexandre Mouravlev

http://www.w3.org/2001/XMLSchema#string

Matthew J During

http://www.w3.org/2001/XMLSchema#string

Patricia A Lawlor

http://www.w3.org/2001/XMLSchema#string

Ross J Bland

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P2860

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

Combined injection of rAAV with mannitol enhances gene expression in the rat brain.

Adeno-associated virus serotypes: vector toolkit for human gene therapy.

Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain.

Clades of Adeno-associated viruses are widely disseminated in human tissues.

AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method

Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins.

Astrocyte activation and reactive gliosis.

Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats

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1692-1702

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10.1038/MT.2009.170

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10

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17

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19638961

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2835020

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