High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors - Wikidata - awgldk - TriplyDB

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

http://www.wikidata.org/entity/Q33713361

about

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells Adeno-associated virus for cystic fibrosis gene therapy AAV-mediated gene therapy in mouse models of recessive retinal degeneration Dawn of ocular gene therapy: implications for molecular diagnosis in retinal disease Corneal gene therapy: basic science and translational perspective In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors Polymers for improving the in vivo transduction efficiency of AAV2 vectors Review: the history and role of naturally occurring mouse models with Pde6b mutations Gene therapy prevents photoreceptor death and preserves retinal function in a Bardet-Biedl syndrome mouse model.3D Imaging of Axons in Transparent Spinal Cords from Rodents and Nonhuman Primates(,.)AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane.Gene therapy in the cornea: 2005--present.Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function Molecular evolution of adeno-associated virus for enhanced glial gene delivery.Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.AAV's anatomy: roadmap for optimizing vectors for translational success Systemic gene delivery to the central nervous system using Adeno-associated virus.Self-complementary AAV5 vector facilitates quicker transgene expression in photoreceptor and retinal pigment epithelial cells of normal mouse.Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs.Gene therapy with mitochondrial heat shock protein 70 suppresses visual loss and optic atrophy in experimental autoimmune encephalomyelitis.An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1α Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injection High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3 Curing color blindness--mice and nonhuman primates Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.Vector platforms for gene therapy of inherited retinopathies.Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogs Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina A single intravenous AAV9 injection mediates bilateral gene transfer to the adult mouse retina.Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice Intravitreal injection of AAV2 transduces macaque inner retina AAV-mediated, optogenetic ablation of Müller Glia leads to structural and functional changes in the mouse retina Optogenetics for retinal disorders Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2.

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P2860

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

http://www.wikidata.org/entity/Q33713361

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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type

label

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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prefLabel

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

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Molecular Therapy

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

@en

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Alfred S Lewin

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Arun Srivastava

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Astra Dinculescu

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Hilda Petrs-Silva

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Ji-Jing Pang

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Li Zhong

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Qiuhong Li

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Seok-Hong Min

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Sergei Zolotukhin

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Vince Chiodo

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P2860

Adeno-associated virus type 2-mediated gene transfer: role of cellular FKBP52 protein in transgene expression

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Adeno-associated virus: from defective virus to effective vector

Effect of gene therapy on visual function in Leber's congenital amaurosis

Adeno-associated virus serotypes: vector toolkit for human gene therapy.

Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer

Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain.

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463-471

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10.1038/MT.2008.269

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3

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17

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Astra Dinculescu

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2008-12-16T00:00:00Z

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23641961

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19066593

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2835095

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