Growth factor independence and BCR/ABL transformation: promise and pitfalls of murine model systems and assays.
about
Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in miceROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice.Dissecting the molecular mechanism of chronic myelogenous leukemia using murine models.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factorFoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.Molecular and cellular bases of chronic myeloid leukemia.Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia.Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens.hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis.Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning.A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.Abnormal growth factor modulation of beta1-integrin-mediated adhesion in chronic myelogenous leukaemia haematopoietic progenitors.p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases.
P2860
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P2860
Growth factor independence and BCR/ABL transformation: promise and pitfalls of murine model systems and assays.
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Growth factor independence and ...... rine model systems and assays.
@ast
Growth factor independence and ...... rine model systems and assays.
@en
type
label
Growth factor independence and ...... rine model systems and assays.
@ast
Growth factor independence and ...... rine model systems and assays.
@en
prefLabel
Growth factor independence and ...... rine model systems and assays.
@ast
Growth factor independence and ...... rine model systems and assays.
@en
P356
P1433
P1476
Growth factor independence and ...... rine model systems and assays.
@en
P2093
P2888
P304
P356
10.1038/SJ/LEU/2401467
P577
1999-08-01T00:00:00Z
P6179
1056650449