Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
about
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansRamadan Fasting and Patients with Cancer: State-of-the-Art and Future ProspectsDietary Restriction and Nutrient Balance in AgingDysregulated metabolism contributes to oncogenesisBenefits of short-term dietary restriction in mammalsGrowth factors, nutrient signaling, and cardiovascular agingRapalogs in cancer prevention: anti-aging or anticancer?Fasting enhances the response of glioma to chemo- and radiotherapyDietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancerTumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor TherapyEnhanced Therapeutic Efficacy in Cancer Patients by Short-term Fasting: The Autophagy ConnectionFasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.Fasting increases the in vivo gene delivery of AAV vectors.Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.Fasting and differential chemotherapy protection in patientsFasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancyThe metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 clusterIGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice.Can short-term fasting protect against doxorubicin-induced cardiotoxicity?Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients.Fasting: molecular mechanisms and clinical applications.Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatinZoledronate Attenuates Accumulation of DNA Damage in Mesenchymal Stem Cells and Protects Their Function.The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.Insulin-like growth factor system and sporadic malignant melanoma.The ketogenic diet for the treatment of malignant glioma.Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivoExploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell cultureFasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.Safety and feasibility of fasting in combination with platinum-based chemotherapyEffect of a low-fat diet combined with IGF-1 receptor blockade on 22Rv1 prostate cancer xenograftsThe Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice.Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy.Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01)Nutrient restriction and radiation therapy for cancer treatment: when less is moreStarvation, detoxification, and multidrug resistance in cancer therapyNRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction.Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma.
P2860
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P2860
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@ast
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@en
type
label
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@ast
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@en
prefLabel
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@ast
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@en
P2093
P2860
P50
P1433
P1476
Reduced levels of IGF-I mediat ...... improve chemotherapeutic index
@en
P2093
Changhan Lee
David Hwang
Federica Madia
Fernando M Safdie
Pinchas Cohen
Valter D Longo
P2860
P304
P356
10.1158/0008-5472.CAN-09-3228
P407
P577
2010-02-09T00:00:00Z