Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo
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Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationCancer stem cells--important players in tumor therapy resistanceTargeting lung cancer through inhibition of checkpoint kinases.UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome.The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence.Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.Combination of lentivirus-mediated silencing of PPM1D and temozolomide chemotherapy eradicates malignant glioma through cell apoptosis and cell cycle arrest.Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy.Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts.AKT/GSK3β Signaling in Glioblastoma.Detection of phosphorylated insulin receptor in colorectal adenoma and adenocarcinoma: implications for prognosis and clinical outcome.Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy.Chemical Proteomic Approaches Targeting Cancer Stem Cells: A Review of Current Literature.Targeting PDK1 for Chemosensitization of Cancer Cells.EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest.DNA Repair.The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.STK3 is a therapeutic target for a subset of acute myeloid leukemias.Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosisNew Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective
P2860
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P2860
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
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Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@en
type
label
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@ast
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@en
prefLabel
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@ast
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@en
P2093
P2860
P50
P356
P1476
Combined PDK1 and CHK1 inhibit ...... ike cells in vitro and in vivo
@en
P2093
E F Petricoin
F Pelacchi
L Morgante
L Stancato
R De Maria
S Giannetti
S di Martino
P2860
P356
10.1038/CDDIS.2014.188
P577
2014-05-08T00:00:00Z