How similar are P450s and what can their differences teach us?
about
Cytochromes P450: a success storyMembrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active siteComparative analysis of P450 signature motifs EXXR and CXG in the large and diverse kingdom of fungi: identification of evolutionarily conserved amino acid patterns characteristic of P450 familyCrystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitorsPreliminary characterization and crystal structure of a thermostable cytochrome P450 from Thermus thermophilusThe 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systemsCrystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesisStructural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesisEvolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact pointsFungal cytochrome p450 monooxygenases: their distribution, structure, functions, family expansion, and evolutionary originCytochromes p450Cytochromes p450Key substrate recognition residues in the active site of a plant cytochrome P450, CYP73A1. Homology guided site-directed mutagenesis.The cytochrome P450 engineering database: Integration of biochemical properties.Genome-wide identification and characterization of cytochrome P450 monooxygenase genes in the ciliate Tetrahymena thermophila.Biological spectra analysis: Linking biological activity profiles to molecular structure.Prediction and analysis of the modular structure of cytochrome P450 monooxygenases.Cytochrome P450(cin) (CYP176A), isolation, expression, and characterization.Key amino acid residues required for aryl migration catalysed by the cytochrome P450 2-hydroxyisoflavanone synthase.MutaCYP: Classification of missense mutations in human cytochromes P450A single amino acid substitution (F363I) converts the regiochemistry of the spearmint (-)-limonene hydroxylase from a C6- to a C3-hydroxylaseOnpA, an unusual flavin-dependent monooxygenase containing a cytochrome b(5) domain.Genome-Wide Analysis, Classification, Evolution, and Expression Analysis of the Cytochrome P450 93 Family in Land Plants.The Localization of Cytochrome P450s CYP1A1 and CYP1A2 into Different Lipid Microdomains Is Governed by Their N-terminal and Internal Protein Regions.Structural and functional divergence of insect CYP6B proteins: From specialist to generalist cytochrome P450Evolutionary origins, molecular cloning and expression of carotenoid hydroxylases in eukaryotic photosynthetic algae.Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbonsFunctional analysis of CYP6ER1, a P450 gene associated with imidacloprid resistance in Nilaparvata lugens.The Cytochrome P450 3A4 Has Three Major Conformations: New Clues to Drug Recognition by this Promiscuous Enzyme.Mechanism of the plant cytochrome P450 for herbicide resistance: a modelling study.Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohliiCompared effect of immunosuppressive drugs cyclosporine A and rapamycin on cholesterol homeostasis key enzymes CYP27A1 and HMG-CoA reductase.Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25].Allelic variation in the Depressaria pastinacella CYP6AB3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential interactions with cytochrome P450 reductase.Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development.Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristicsCopper enhanced monooxygenase activity and FT-IR spectroscopic characterisation of biotransformation products in trichloroethylene degrading bacterium: Stenotrophomonas maltophilia PM102.
P2860
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P2860
How similar are P450s and what can their differences teach us?
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
How similar are P450s and what can their differences teach us?
@ast
How similar are P450s and what can their differences teach us?
@en
type
label
How similar are P450s and what can their differences teach us?
@ast
How similar are P450s and what can their differences teach us?
@en
prefLabel
How similar are P450s and what can their differences teach us?
@ast
How similar are P450s and what can their differences teach us?
@en
P356
P1476
How similar are P450s and what can their differences teach us?
@en
P2093
Peterson JA
P356
10.1006/ABBI.1999.1350
P407
P577
1999-09-01T00:00:00Z