Galectins: an evolutionarily conserved family of animal lectins with multifunctional properties; a trip from the gene to clinical therapy.
about
Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashionExpression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiensGalectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor.The role of galectin-4 in physiology and diseases.Galectin-3: its role in asthma and potential as an anti-inflammatory targetStructural basis of multivalent galactose-based dendrimer recognition by human galectin-7Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocationPotential roles of galectins in myeloid differentiation into three different lineagesProtein targets of monocrotaline pyrrole in pulmonary artery endothelial cells.Identification of galectin-7 as a potential biomarker for esophageal squamous cell carcinoma by proteomic analysisGlycohistochemistry: the why and how of detection and localization of endogenous lectins.A glycobiology review: carbohydrates, lectins and implications in cancer therapeuticsGalectin-1 overexpression in endometriosis and its regulation by neuropeptides (CRH, UCN) indicating its important role in reproduction and inflammationCritical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma.Enterovirus 71 virion-associated galectin-1 facilitates viral replication and stabilityDendritic cell-derived exosomes express a Streptococcus pneumoniae capsular polysaccharide type 14 cross-reactive antigen that induces protective immunoglobulin responses against pneumococcal infection in mice.Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection.The role of galectins in the initiation, amplification and resolution of the inflammatory response.Endogenous galectin-1 enforces class I-restricted TCR functional fate decisions in thymocytes.Glycobiology of cell death: when glycans and lectins govern cell fate.Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation.Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation.Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke.Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands.The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2.Gene expression profiling of the early pulmonary response to hyperoxia in mice.Regulated expression and effect of galectin-1 on Trypanosoma cruzi-infected macrophages: modulation of microbicidal activity and survival.Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways.A modified version of galectin-9 induces cell cycle arrest and apoptosis of Burkitt and Hodgkin lymphoma cells.Microarray gene expression profiling of cell lines from primary and metastatic tongue squamous cell carcinoma: possible insights from emerging technology.Pharmacological inhibition of galectin-3 protects against hypertensive nephropathy.Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3.Cell cycle regulation by galectin-12, a new member of the galectin superfamily.Characterization of a novel Drosophila melanogaster galectin. Expression in developing immune, neural, and muscle tissues.Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma.Galectin-7 in Epithelial Homeostasis and Carcinomas.Cypermethrin exposure leads to regulation of proteins expression involved in neoplastic transformation in mouse skin.Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis.Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.
P2860
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P2860
Galectins: an evolutionarily conserved family of animal lectins with multifunctional properties; a trip from the gene to clinical therapy.
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@ast
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@en
type
label
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@ast
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@en
prefLabel
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@ast
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@en
P356
P1476
Galectins: an evolutionarily c ...... the gene to clinical therapy.
@en
P2093
Rabinovich GA
P2888
P304
P356
10.1038/SJ.CDD.4400535
P577
1999-08-01T00:00:00Z
P5875
P6179
1017432626