Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
about
Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stressGenome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.Epigenetics in Alzheimer's Disease: Perspective of DNA Methylation.Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.What is the evidence that tau pathology spreads through prion-like propagation?Pseudoexfoliation and Alzheimer's associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression.Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain.An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.Genetics of Alzheimer's Disease: the Importance of Polygenic and Epistatic Components.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn.Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease.Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS SignalsEarly Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review
P2860
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P2860
Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Functional screening of Alzhei ...... early marker of Tau pathology.
@ast
Functional screening of Alzhei ...... early marker of Tau pathology.
@en
type
label
Functional screening of Alzhei ...... early marker of Tau pathology.
@ast
Functional screening of Alzhei ...... early marker of Tau pathology.
@en
prefLabel
Functional screening of Alzhei ...... early marker of Tau pathology.
@ast
Functional screening of Alzhei ...... early marker of Tau pathology.
@en
P2093
P2860
P50
P356
P1433
P1476
Functional screening of Alzhei ...... early marker of Tau pathology
@en
P2093
A Bretteville
B Grenier-Boley
F Abdelfettah
H Soininen
M Hiltunen
P2860
P2888
P304
P356
10.1038/MP.2016.59
P407
P50
P577
2016-04-26T00:00:00Z