SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
about
SIRT1 ameliorates oxidative stress induced neural cell death and is down-regulated in Parkinson's disease.Individually tailored screening of susceptibility to sarcopenia using p53 codon 72 polymorphism, phenotypes, and conventional risk factorsModelling and analysis of the feeding regimen induced entrainment of hepatocyte circadian oscillators using petri netsA small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activityHuR and TIA1/TIAL1 are involved in regulation of alternative splicing of SIRT1 pre-mRNA.The dual role of sirtuins in cancer.The influence of Argonaute proteins on alternative RNA splicing.The emerging role of alternative splicing in senescence and aging.A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes.Autophagy regulating kinases as potential therapeutic targets for age-related macular degeneration.Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways.Identification of a Tissue-Restricted Isoform of SIRT1 Defines a Regulatory Domain that Encodes Specificity.RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3' Nuclease-resistant Mini-hairpin Structure.Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation.MicroRNA-34a regulates proliferation and apoptosis of gastric cancer cells by targeting silent information regulator 1.Distinct patterns of sirtuin expression during progression of Alzheimer's disease.
P2860
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P2860
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@ast
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@en
type
label
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@ast
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@en
prefLabel
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@ast
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@en
P2093
P2860
P50
P1433
P1476
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
@en
P2093
Cian J Lynch
Lorna J Warnock
Shafiq U Ahmed
P2860
P304
P356
10.1371/JOURNAL.PONE.0013502
P407
P577
2010-10-21T00:00:00Z