Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
about
ATM substrate Chk2-interacting Zn2+ finger (ASCIZ) Is a bi-functional transcriptional activator and feedback sensor in the regulation of dynein light chain (DYNLL1) expressionATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.Atmin mediates kidney morphogenesis by modulating Wnt signaling.ATM signalling and cancer.Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.The novel zinc finger protein dASCIZ regulates mitosis in Drosophila via an essential role in dynein light-chain expressionASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.ATMIN: a new tumor suppressor in developing B cells.ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.Multivalency regulates activity in an intrinsically disordered transcription factor.
P2860
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P2860
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
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2010 nî lūn-bûn
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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@ast
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
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type
label
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@ast
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@en
prefLabel
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@ast
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@en
P2093
P2860
P1433
P1476
Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis
@en
P2093
Andrew Hammet
Bryce van Denderen
Carolyn J McNees
Hayato Oka
Jane-Lee Ng
Ken-Ichi Yamamoto
Kimberly Hewitt
Lindus A Conlan
Martin F Lavin
P2860
P304
P356
10.1371/JOURNAL.PGEN.1001170
P577
2010-10-21T00:00:00Z