Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation

Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation

Item
http://www.wikidata.org/entity/Q33731432
Nicotinamide protects hepatocytes against palmitate-induced lipotoxicity via SIRT1-dependent autophagy induction.Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells.Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis.Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule.The Inhibitory Effects of Purple Sweet Potato Color on Hepatic Inflammation Is Associated with Restoration of NAD⁺ Levels and Attenuation of NLRP3 Inflammasome Activation in High-Fat-Diet-Treated Mice.The TLR4-IRE1α pathway activation contributes to palmitate-elicited lipotoxicity in hepatocytes.
P2860

Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation

Item
http://www.wikidata.org/entity/Q33731432
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@ast
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@en
type
label
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@ast
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@en
prefLabel
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@ast
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Nicotinamide ameliorates palmi ...... y-dependent Sirt1 upregulation
@en
P2093
P2860
P304
P31
P356
10.1016/J.BBAMCR.2015.09.003
P407
P433
P478
P577
P698
P932