Conotoxins targeting nicotinic acetylcholine receptors: an overview
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Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRsA Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA.Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding.Cone snail venomics: from novel biology to novel therapeutics.Structural and Functional Characterization of a Novel α-Conotoxin Mr1.7 from Conus marmoreus Targeting Neuronal nAChR α3β2, α9α10 and α6/α3β2β3 Subtypes.Molecular Diversity and Gene Evolution of the Venom Arsenal of Terebridae Predatory Marine Snails.A novel 4/6-type alpha-conotoxin ViIA selectively inhibits nAchR α3β2 subtype.αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR.High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method.Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.Natural compounds interacting with nicotinic acetylcholine receptors: from low-molecular weight ones to peptides and proteins.Therapeutic conotoxins: a US patent literature survey.Animal venom studies: Current benefits and future developmentsα-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition.Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins.The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypesConotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors.RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.Molecular Engineering of Conus Peptides as Therapeutic Leads.G-Protein Coupled Receptors Targeted by Analgesic Venom Peptides.Aqueous ionic liquids influence the disulfide bond isoform equilibrium in conotoxin AuIB: a consequence of the Hofmeister effect?A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity.Venom based neural modulators.Cloning, Synthesis and Functional Characterization of a Novel α-Conotoxin Lt1.3.Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails.A 3D structural model of RsXXVIA, an ω-conotoxin
P2860
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P2860
Conotoxins targeting nicotinic acetylcholine receptors: an overview
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@ast
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@en
type
label
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@ast
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@en
prefLabel
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@ast
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@en
P2093
P2860
P921
P356
P1433
P1476
Conotoxins targeting nicotinic acetylcholine receptors: an overview
@en
P2093
Isuru Wijesekara
Jan Tytgat
Steve Peigneur
P2860
P304
P356
10.3390/MD12052970
P577
2014-05-22T00:00:00Z