IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
about
The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineThe human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membraneSignaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNFSolution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complexInactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patientGeneration of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationStructure of the extracellular domains of the human interleukin-6 receptor alpha -chainThe N-terminal cytokine binding domain of LIFR is required for CNTF binding and signalingInterleukin-11 signals through the formation of a hexameric receptor complexMembrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitroAbrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage displayCharacterization of a potent human interleukin-11 agonistA ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11.Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro.Receptor recognition by gp130 cytokines.Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells.Functional characterization of W147A: a high-affinity interleukin-11 antagonistDifferent associations of CD45 isoforms with STAT3, PKC and ERK regulate IL-6-induced proliferation in myeloma.Interleukin-6 in aging and chronic disease: a magnificent pathwayThe IL-6/sIL-6R complex as a novel target for therapeutic approaches.IL-6/IL-6 receptor system and its role in physiological and pathological conditions.IL-11 signaling as a therapeutic target for cancer.The role and therapeutic targeting of IL-6 in rheumatoid arthritis.Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation.Serum amyloid A 2.2 refolds into a octameric oligomer that slowly converts to a more stable hexamer.Leukemia inhibitory factor (LIF), cardiotrophin-1, and oncostatin M share structural binding determinants in the immunoglobulin-like domain of LIF receptor.Separate functions for the two modules of the membrane-proximal cytokine binding domain of glycoprotein 190, the leukemia inhibitory factor low affinity receptor, in ligand binding and receptor activation.C-terminal peptides of interleukin-6 modulate the expression of junB protooncogene and the production of fibrinogen by HepG2 cells.Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor.Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane.Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6.Interleukin-6 N-terminal peptides modulate the expression of junB protooncogene and the production of fibrinogen in HepG2 cells.Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.Synthetic Mimetics of the gp130 Binding Site for Viral Interleukin-6 as Inhibitors of the vIL-6-gp130 Interaction
P2860
Q24291080-5E293EDB-6125-4E3B-AAF0-37FB8973BB50Q24297675-C7FB101E-AEA4-4DA1-9BC5-2BB8E66157DEQ24297991-D63A483A-725C-4469-91E0-E22ADFBC6D7FQ24300314-C1907D9F-5267-4BB3-A4A5-DDA3141B512EQ24550951-A7BF9FF7-7B43-4453-8634-6E831D63D2F1Q26738992-19AD6972-B7E3-4F45-909C-2C451F0CD589Q27640083-BF97C94D-E8CE-476B-8183-509FD3D3FAAEQ28119167-35499351-5193-4CE9-B673-E594B1D7F190Q28144068-73DBA533-4D35-4431-9703-8CC68D94515AQ28627093-8ABD067F-B4F1-44DC-91C0-F53BFCE2953EQ33254113-E92D5818-BCCF-4F37-8846-06B32DA99D0CQ33349514-C97621AA-C3CC-45F8-B484-17B3D8634C6CQ33378529-25E0ADE6-0B4D-46C7-A2D1-95B8D42B1ECDQ33877006-5B25C8B6-9C92-4132-8F4A-FD157C873914Q33931723-3D490B48-0B39-40AE-8C63-C1946603F2F4Q34102346-AB14D0EE-C66A-4AE0-8305-F8853425F046Q35113678-AEA557B5-2B0B-4662-B1B3-995D678EEDB4Q35579670-C459956B-5143-4E35-8C2D-98627F1D95F6Q36518670-7153FE62-0BB7-4754-BE6A-D6B8DAE82B0EQ36804420-1A8A0314-FBF7-4DFD-9B39-F30F0A70A111Q37949664-80E54C43-EFA4-4587-B747-333420B12256Q38445355-0FF8D179-2FCC-4A05-A1C3-13118D26DC1AQ38685086-4E89B2C1-5D4D-48D0-8520-E7480EA67E50Q38718364-82E3B9F6-B389-4E61-9D21-9CEE00623DE0Q39992202-6765D73E-91CD-4EE5-8E76-F175EAC70609Q40653268-1C8763A5-8B19-42F1-B6B0-51D1D8AD00F7Q40752177-E44DE8D8-5FBD-4F64-911E-75E74238C44CQ40798848-933C4E0E-0BAB-4277-BE5D-B16023EE9338Q41839982-5620E427-184A-4930-89D0-DDC46D55E0B3Q42158045-9E10963A-17F4-4D50-A12B-D7977D6EEC12Q45007823-41035F91-D697-49AA-BC6C-D7F8782D7F68Q47951600-81C1DA6C-29F7-4E06-914D-787B03C58600Q51787521-171452DC-B3E0-44BD-9369-E12A284B1244Q57339910-D2A8A26A-7C80-453A-89B4-D06AB7AA168B
P2860
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@ast
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@en
type
label
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@ast
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@en
prefLabel
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@ast
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@en
P2093
P2860
P356
P1433
P1476
IL-6 type cytokine receptor complexes: hexamer, tetramer or both?
@en
P2093
Grötzinger J
Kernebeck T
P2860
P304
P356
10.1515/BC.1999.100
P577
1999-07-01T00:00:00Z