CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies
about
Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States.Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies.Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation.CD4 mimetics sensitize HIV-1-infected cells to ADCC.Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.The Yin and Yang of ADCC-Mediating Antibodies.Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated CytotoxicitySmall-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds.Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.Driving HIV-1 into a Vulnerable Corner by Taking Advantage of Viral Adaptation and Evolution.Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors.Double Variational Binding--(SMILES) Conformational Analysis by Docking Mechanisms for Anti-HIV Pyrimidine Ligands.Uncovering HIV-1-infected cells.Comparison of Uncleaved and Mature Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimers.A Small-Molecule CD4-mimetic Compound Protects BLT Humanized Mice from Human Immunodeficiency Virus Infection.A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.
P2860
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P2860
CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@ast
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@en
type
label
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@ast
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@en
prefLabel
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@ast
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@en
P2093
P2860
P356
P1433
P1476
CD4-mimetic small molecules se ...... to vaccine-elicited antibodies
@en
P2093
Amos B Smith
Amy M Princiotto
Arne Schön
David M Jones
Ernesto Freire
Hua-Xin Liao
James Robinson
Joel R Courter
Jongwoo Park
Judith LaLonde
P2860
P304
P356
10.1128/JVI.00540-14
P577
2014-04-02T00:00:00Z