Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage.
about
Complement cascade and kidney transplantation: The rediscovery of an ancient enemyThe role of complement in the pathogenesis of renal ischemia-reperfusion injury and fibrosisEffector mechanisms of rejectionMannan-binding lectin in cardiovascular disease.Review: Complement and its regulatory proteins in kidney diseases.Value of plasmatic membrane attack complex as a marker of severity in acute kidney injuryImpact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction: a post-hoc analysis of a multicenter randomized controlled trial.Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasisRenoprotective Mechanism of Remote Ischemic Preconditioning Based on Transcriptomic Analysis in a Porcine Renal Ischemia Reperfusion Injury Model.Potential role of the lectin pathway of complement in the pathogenesis and disease manifestations of systemic sclerosis: a case-control and cohort study.Heme interacts with c1q and inhibits the classical complement pathway.Enhancing complement control on endothelial barrier reduces renal post-ischemia dysfunctionComplement involvement in kidney diseases: From physiopathology to therapeutical targetingUnilateral uterine ischemia/reperfusion-induced bilateral fetal loss and fetal growth restriction in a murine model require intact complement component 5.Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation.Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.The role of the complement system in acute kidney injury.Inhibition of complement improves graft outcome in a pig model of kidney autotransplantation.Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction.Role of complement and perspectives for intervention in ischemia-reperfusion damage.New strategies to optimize kidney recovery and preservation in transplantation.Overview of complement activation and regulationUpdate on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment.Role of complement in glomerular diseases.Targeted complement inhibition and microvasculature in transplants: a therapeutic perspective.Innate Immunity in Systemic Sclerosis.Complement in ANCA-associated vasculitis: mechanisms and implications for management.Delayed graft function and its management in children.Macrophages as Effectors of Acute and Chronic Allograft Injury.Natural IgM antibodies are involved in the activation of complement by hypoxic human tubular cells.New insight into the effects of heparinoids on complement inhibition by C1-inhibitor.Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function.Thrombin may modulate dendritic cell activation in kidney transplant recipients with delayed graft function.Which pathways trigger the role of complement in ischaemia/reperfusion injury?Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice.Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway.Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms.Emerging biomarkers in renal damage.Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.
P2860
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P2860
Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Therapeutic targeting of class ...... erfusion-induced renal damage.
@ast
Therapeutic targeting of class ...... erfusion-induced renal damage.
@en
type
label
Therapeutic targeting of class ...... erfusion-induced renal damage.
@ast
Therapeutic targeting of class ...... erfusion-induced renal damage.
@en
prefLabel
Therapeutic targeting of class ...... erfusion-induced renal damage.
@ast
Therapeutic targeting of class ...... erfusion-induced renal damage.
@en
P2093
P2860
P50
P1476
Therapeutic targeting of class ...... erfusion-induced renal damage.
@en
P2093
Antonia Loverre
Francesco Paolo Schena
Francesco Paolo Selvaggi
Gennaro Annunziata
Giuseppe Grandaliano
Maurice Mannesse
Michele Rossini
Mohamed R Daha
Pasquale Ditonno
Rita Melchiorre
P2860
P304
P356
10.2353/AJPATH.2010.090276
P407
P50
P577
2010-02-11T00:00:00Z