The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.

The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.

Item
http://www.wikidata.org/entity/Q33746340
Review of P-gp inhibition data in recently approved new drug applications: utility of the proposed [I(1) ]/IC(50) and [I(2) ]/IC(50) criteria in the P-gp decision tree.Drug-permeability and transporter assays in Caco-2 and MDCK cell lines.Advances in epilepsy treatment: lacosamide pharmacokinetic profile.MDR1 and OAT1/OAT3 mediate the drug-drug interaction between puerarin and methotrexate.Use of different parameters and equations for calculation of IC₅₀ values in efflux assays: potential sources of variability in IC₅₀ determination.Clarification of P-glycoprotein inhibition-related drug-drug interaction risks based on a literature search of the clinical information.Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure.Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
P2860

The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.

Item
http://www.wikidata.org/entity/Q33746340
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The utility of in vitro data i ...... ons: a case study for AZD5672.
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The utility of in vitro data i ...... ons: a case study for AZD5672.
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type
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The utility of in vitro data i ...... ons: a case study for AZD5672.
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The utility of in vitro data i ...... ons: a case study for AZD5672.
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The utility of in vitro data i ...... ons: a case study for AZD5672.
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The utility of in vitro data i ...... ons: a case study for AZD5672.
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P2093
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P1476
The utility of in vitro data i ...... ons: a case study for AZD5672.
@en
P2093
P304
P31
P356
P433
P478
P577
P698