The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. - Wikidata - awgldk - TriplyDB

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

http://www.wikidata.org/entity/Q33748190

about

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6 International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2 Activated Complement Factors as Disease Markers for Sepsis Multifaceted role of β-arrestins in inflammation and disease Complement and macrophage crosstalk during process of angiogenesis in tumor progression The inflammatory response in sepsis Obstacles in haemocompatibility testing N-formyl peptide receptor 3 (FPR3) departs from the homologous FPR2/ALX receptor with regard to the major processes governing chemoattractant receptor regulation, expression at the cell surface, and phosphorylation Complement System Part II: Role in Immunity Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells Complement: a key system for immune surveillance and homeostasis The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Anaphylatoxin C5a modulates hepatic stellate cell migration The Controversial C5a Receptor C5aR2: Its Role in Health and Disease.Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia Requirements for membrane attack complex formation and anaphylatoxins binding to collagen-activated platelets.Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.Complement anaphylatoxins as immune regulators in cancer.Recombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanisms.C5a receptor deficiency alters energy utilization and fat storage.A pro-inflammatory role of C5L2 in C5a-primed neutrophils for ANCA-induced activation.Association of C5aR1genetic polymorphisms with coronary artery disease in a Han population in Xinjiang, China CD66b Overexpression and Loss of C5a Receptors as Surface Markers for Staphylococcus aureus-Induced Neutrophil Dysfunction C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity.Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis Interactions between coagulation and complement--their role in inflammation C5a and toll-like receptor 4 crosstalk in retinal pigment epithelial cells.A novel role of complement in retinal degeneration.Complement-targeted therapeutics in periodontitis Complement activation, regulation, and molecular basis for complement-related diseases Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection.Innate Immune Signaling Activated by MDR Bacteria in the Airway C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay.Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology.A Novel Role for the Receptor of the Complement Cleavage Fragment C5a, C5aR1, in CCR5-Mediated Entry of HIV into Macrophages.C5a inhibitor protects against ischemia/reperfusion injury in rat small intestine

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The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

http://www.wikidata.org/entity/Q33748190

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

@ast

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

@en

type

label

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

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The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

@en

prefLabel

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

@ast

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

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JBC.M109.092106

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Journal of Biological Chemistry

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The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction

@en

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Bao Lu

http://www.w3.org/2001/XMLSchema#string

Claire E Bamberg

http://www.w3.org/2001/XMLSchema#string

Craig Gerard

http://www.w3.org/2001/XMLSchema#string

David Zahra

http://www.w3.org/2001/XMLSchema#string

Hyun Lee

http://www.w3.org/2001/XMLSchema#string

Jenny Jackson

http://www.w3.org/2001/XMLSchema#string

Norma P Gerard

http://www.w3.org/2001/XMLSchema#string

Peter L Whitfeld

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Stewart Craig

http://www.w3.org/2001/XMLSchema#string

Yun Si Lim

http://www.w3.org/2001/XMLSchema#string

P2860

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein

C5L2 is a functional receptor for acylation-stimulating protein

Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis

An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

Function, structure and therapeutic potential of complement C5a receptors

A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)

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7633-7644

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scholarly article

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10.1074/JBC.M109.092106

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10

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285

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Charles R. Mackay

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2009-12-31T00:00:00Z

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40821716

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20044484

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2844210

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