Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP. - Wikidata - awgldk - TriplyDB

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

http://www.wikidata.org/entity/Q33754831

about

Protein trafficking abnormalities in Drosophila tissues with impaired activity of the ZIP7 zinc transporter Catsup Synaptic abnormalities in a Drosophila model of Alzheimer's disease Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development.Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease.Notch signaling in pancreatic cancer: oncogene or tumor suppressor?Novel and facile synthesis of 1-benzazepines via copper-catalyzed oxidative C(sp3)-H/C(sp2)-H cross-coupling.A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma.Transcriptomic Analysis of Drosophila Mushroom Body Neurons Lacking Amyloid-β Precursor-Like Protein Activity.

P2860

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P2860

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

http://www.wikidata.org/entity/Q33754831

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

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Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

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type

label

Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

@ast

Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

@en

prefLabel

Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

@ast

Pharmacological analysis of Dr ...... proteolysis of Notch and APP.

@en

P1433

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P1433

Molecular Pharmacology

P1476

Pharmacological analysis of Dr ...... l proteolysis of Notch and APP

@en

P2093

Mark E Fortini

http://www.w3.org/2001/XMLSchema#string

Octavio A Quiñones

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W Gregory Alvord

http://www.w3.org/2001/XMLSchema#string

P2860

Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment.

The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

Identification of distinct gamma-secretase complexes with different APH-1 variants

Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities

Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity

Calcium depletion dissociates and activates heterodimeric notch receptors

The canonical Notch signaling pathway: unfolding the activation mechanism.

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Effect of valine on the efficiency and precision at S4 cleavage of the Notch-1 transmembrane domain.

What the evolution of the amyloid protein precursor supergene family tells us about its function.

P304

567-574

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P31

scholarly article

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10.1124/MOL.109.062471

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4

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77

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2010-01-11T00:00:00Z

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40907566

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20064975

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P921

Drosophila melanogaster

P932

2845938

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