Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
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Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal modelIncreased B and T Cell Responses in M. bovis Bacille Calmette-Guérin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis AntigenFailure to induce enhanced protection against tuberculosis by increasing T-cell-dependent interferon-gamma generationMycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infectionAttenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosisIdentification of a Mycobacterium bovis BCG auxotrophic mutant that protects guinea pigs against M. bovis and hematogenous spread of Mycobacterium tuberculosis without sensitization to tuberculin.Identification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening.Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and interleukin-2 for protection against bovine tuberculosisRecombinant guinea pig tumor necrosis factor alpha stimulates the expression of interleukin-12 and the inhibition of Mycobacterium tuberculosis growth in macrophages.Effective, nonsensitizing vaccination with culture filtrate proteins against virulent Mycobacterium bovis infections in mice.Peripheral blood and pleural fluid mononuclear cell responses to low-molecular-mass secretory polypeptides of Mycobacterium tuberculosis in human models of immunity to tuberculosis.Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG alone.bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs.Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research.Pulmonary immunization using antigen 85-B polymeric microparticles to boost tuberculosis immunity.Pathophysiology of antigen 85 in patients with active tuberculosis: antigen 85 circulates as complexes with fibronectin and immunoglobulin G.Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences.Interleukin-6 and interleukin-12 participate in induction of a type 1 protective T-cell response during vaccination with a tuberculosis subunit vaccine.ESAT-6 subunit vaccination against Mycobacterium tuberculosisEffective preexposure tuberculosis vaccines fail to protect when they are given in an immunotherapeutic mode.DNA vaccination against tuberculosis: expression of a ubiquitin-conjugated tuberculosis protein enhances antimycobacterial immunity.Lack of protection in mice and necrotizing bronchointerstitial pneumonia with bronchiolitis in guinea pigs immunized with vaccines directed against the hsp60 molecule of Mycobacterium tuberculosisBoosting vaccine for tuberculosis.Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and esat-6.Antigen specificity of T-cell response to Mycobacterium avium infection in mice.BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis.Vaccination with a Sindbis virus-based DNA vaccine expressing antigen 85B induces protective immunity against Mycobacterium tuberculosis.DNA vaccine combinations expressing either tissue plasminogen activator signal sequence fusion proteins or ubiquitin-conjugated antigens induce sustained protective immunity in a mouse model of pulmonary tuberculosisMycobacterial antigens exacerbate disease manifestations in Mycobacterium tuberculosis-infected mice.Vaccination of guinea pigs with DNA encoding the mycobacterial antigen MPB83 influences pulmonary pathology but not hematogenous spread following aerogenic infection with Mycobacterium bovisDNA immunization in a mouse model of latent tuberculosis: effect of DNA vaccination on reactivation of disease and on reinfection with a secondary challenge.Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosisNeutralization of tumor necrosis factor alpha suppresses antigen-specific type 1 cytokine responses and reverses the inhibition of mycobacterial survival in cocultures of immune guinea pig T lymphocytes and infected macrophages.The ID93 tuberculosis vaccine candidate does not induce sensitivity to purified protein derivative.Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis.On the use of DNA vaccines for the prophylaxis of mycobacterial diseases.Pulmonary necrosis resulting from DNA vaccination against tuberculosis.Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs.The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infectionNonclinical Development of BCG Replacement Vaccine Candidates.
P2860
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P2860
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@ast
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@en
type
label
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@ast
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@en
prefLabel
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@ast
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@en
P2093
P2860
P1476
Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis
@en
P2093
A D Roberts
D M McMurray
S L Baldwin
P2860
P304
P407
P50
P577
1998-06-01T00:00:00Z