PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.
about
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppressionThe role of myofibroblasts in wound healing, contraction and its clinical implications in cleft palate repairInhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblastsProstaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-APPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.Signal transduction pathway analysis in desmoid-type fibromatosis: transforming growth factor-β, COX2 and sex steroid receptorsThe anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibitionNormal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function.Matrices of physiologic stiffness potently inactivate idiopathic pulmonary fibrosis fibroblasts.Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin.Eicosanoid lipid mediators in fibrotic lung diseases: ready for prime time?Reversal of myofibroblast differentiation by prostaglandin E(2).Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis.Emerging concepts in the pathogenesis of lung fibrosisPhosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expressionHepatocyte growth factor in lung repair and pulmonary fibrosis.Cellular and molecular mechanisms of chronic inflammation-associated organ fibrosis.Targeting focal adhesion kinase in fibrotic diseases.Hepatocyte growth factor is an attractive target for the treatment of pulmonary fibrosis.Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection.Transforming Growth Factor-β1 Increases DNA Methyltransferase 1 and 3a Expression through Distinct Post-transcriptional Mechanisms in Lung Fibroblasts.Attenuation of EMT in RPE cells and subretinal fibrosis by an RAR-γ agonist.Microsomal prostaglandin E synthase-1 deficiency exacerbates pulmonary fibrosis induced by bleomycin in mice.Myofibroblast repair mechanisms post-inflammatory response: a fibrotic perspective.Stromal and immune cells in gut fibrosis: the myofibroblast and the scarface.Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration.The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation.Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts.Prostaglandin E(2)-dependent blockade of actomyosin and stress fibre formation is mediated through S1379 phosphorylation of ROCK2.Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta.Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts.Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation.Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury.
P2860
Q24627446-B93BF207-72A5-46B8-B6D5-37B54E01434DQ27023860-C5200B38-B40C-4BC4-B534-DB7171E19928Q31052506-7ED0C004-702C-4C7B-8BAA-776FA16C60C3Q33761334-95AEA871-775F-4BA0-BFF5-072FD74C63EBQ33799182-0DDA1336-C57A-494B-AE63-925032646AFCQ34643472-433F323B-ED60-423B-85F5-D66328878E3AQ35144202-FB2C896E-5488-4337-99A9-04D56E06E75EQ35219865-85AFDEE1-DF0B-4567-9E55-6BEDD3268ECBQ35291689-B5547903-38B0-4D74-AB03-7A879DB42D66Q35738996-11C07C41-8683-49BC-8CC2-7D98C1081749Q36778233-C190FA13-D724-4BAB-A976-3E0DBD038232Q36822323-BF4FA87A-F031-491F-9579-9DC4576E352DQ36842944-EFF53505-589A-4FC6-AF23-30B94D260F70Q36923894-15EA3D10-8A17-453D-B6DA-7A70FE27B862Q36970702-EF386448-CA7F-44F8-9696-9AC65E59FA7AQ36999832-A2E17BE2-1731-4812-9D53-CC954FDD5C03Q37030035-9578C773-F0EF-4445-AB12-2637E255998EQ37257093-B56930E3-06BD-4A45-9A11-97C5ADBCCFA8Q37431908-45A36998-5E6F-4C54-B0E8-B0E9B7EF4E43Q37729853-A199F9FE-3C89-4183-9731-C0834F4B5803Q38008371-2FE193EA-6CD6-4713-A127-2710898310AFQ38074882-1E618DBE-9A38-48DD-B4AC-A1A940FDA406Q38088776-BBFE1990-9562-4504-B8DF-EA92330E3B92Q38713268-D7C9DA73-0A10-48B0-96EB-C00E2AF51B28Q38758532-23B22AC0-B65E-4DAB-81E9-6A4632829D99Q38878484-EE5D7A96-6DF3-4F52-84C1-459A3F2FC9A8Q39001890-49E4C30D-F55B-4336-8903-04A2EC7E9D89Q39063947-533FFCC6-AB5B-4E47-B1D4-6517314EC0D0Q39401444-64EA918B-1EDB-4091-B559-E9FFB4821A49Q39801563-353A4316-0AD4-49A2-856B-5A9C16F53A70Q40794888-66B73C9A-879D-432E-ADB1-038AF0DAD45DQ41949357-E005C86D-4AA2-400A-A29C-EA4AD69E0023Q42144426-B126D641-AE99-448C-AA25-C9D174EFD29CQ42455440-E806FE20-66C4-4FC0-832D-9B9F7B7A0FC2Q42553529-F7DFE8C7-3D47-4F7C-98C2-A8BE75A57C1EQ43008071-0F4425A4-000B-4B36-925B-65961E230A56Q46079226-D6A05911-DE0C-4F85-989D-73F47339F177Q49857850-D8C960C1-95F0-46AF-89A0-72642DA4F99FQ50879214-6A81334A-3029-4549-884D-77AC3C5D14E9Q55387631-AE790198-28EF-43AF-9663-E5197BA6FD9A
P2860
PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@ast
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@en
type
label
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@ast
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@en
prefLabel
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@ast
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@en
P2093
P2860
P1476
PGE(2) inhibition of TGF-beta1 ...... adhesion-dependent signaling.
@en
P2093
Bethany B Moore
Eric S White
Peedikayil E Thomas
Victor J Thannickal
P2860
P304
P356
10.1152/AJPLUNG.00489.2006
P577
2007-06-08T00:00:00Z