Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth - Wikidata - awgldk - TriplyDB

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

http://www.wikidata.org/entity/Q33758338

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Endocrine regulation of energy metabolism by the skeleton Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6 Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferation Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1 Mechanisms of action of glucagon-like peptide 1 in the pancreas Pancreatic β Cell Mass Death Two-way communication between the metabolic and cell cycle machineries: the molecular basis Role of AKT/mTORC1 pathway in pancreatic β-cell proliferation Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis The cell cycle as a brake for β-cell regeneration from embryonic stem cells Insights from exome sequencing for endocrine disorders ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression Dachshund homologues play a conserved role in islet cell development Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells Genetics of Type 2 Diabetes: the Power of Isolated Populations.Islet biology, the CDKN2A/B locus and type 2 diabetes risk.The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.Genome-wide association study for conformation traits in three Danish pig breeds.Metabolism genes are among the differentially expressed ones observed in lymphomononuclear cells of recently diagnosed type 1 diabetes mellitus patients.Increased islet neogenesis without increased islet mass precedes autoimmune attack in diabetes-prone rats.Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas.Absence of p53-dependent apoptosis combined with nonhomologous end-joining deficiency leads to a severe diabetic phenotype in mice.Brd2 disruption in mice causes severe obesity without Type 2 diabetes.Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents Mangiferin facilitates islet regeneration and β-cell proliferation through upregulation of cell cycle and β-cell regeneration regulators.Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease ISL1 promotes pancreatic islet cell proliferation.Genistein induces pancreatic beta-cell proliferation through activation of multiple signaling pathways and prevents insulin-deficient diabetes in mice MafA is required for postnatal proliferation of pancreatic β-cells.Glucose infusion in mice: a new model to induce beta-cell replication.Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes.Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

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Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

http://www.wikidata.org/entity/Q33758338

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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type

label

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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prefLabel

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

@ast

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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MCB.25.9.3752-3762.2005

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Molecular and Cellular Biology

P1476

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

@en

P2093

Ewa Sicinska

http://www.w3.org/2001/XMLSchema#string

Jake A Kushner

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Lynn M Wartschow

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Monica Teta

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Morris F White

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Piotr Sicinski

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Simon Y Long

http://www.w3.org/2001/XMLSchema#string

P2860

Disruption of IRS-2 causes type 2 diabetes in mice

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number

Cyclin E ablation in the mouse

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.

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3752-3762

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10.1128/MCB.25.9.3752-3762.2005

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9

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25

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Maria Ciemerych-Litwinienko

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2005-05-01T00:00:00Z

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7906579

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15831479

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1084308

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