The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. - Wikidata - awgldk - TriplyDB

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

http://www.wikidata.org/entity/Q33762811

about

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol Prolyl isomerase Pin1 in cancer Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons.Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1 Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice.The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils.A distinct role for Pin1 in the induction and maintenance of pluripotency.Pin1 null mice exhibit low bone mass and attenuation of BMP signaling Dusp5 negatively regulates IL-33-mediated eosinophil survival and function D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc.Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.Pin1 protein regulates Smad protein signaling and pulmonary fibrosis.The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.Essential role of Pin1 via STAT3 signalling and mitochondria-dependent pathways in restenosis in type 2 diabetes Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process.Apoptosis and oncogenesis: give and take in the BCL-2 family.Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.Evading apoptosis in cancer.Mitochondria in the center of human eosinophil apoptosis and survival Regulation of spontaneous eosinophil apoptosis-a neglected area of importance.Determinants of eosinophil survival and apoptotic cell death.The role of Pin1 in the development and treatment of cancer.ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis.Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax Cytosolic Bax: does it require binding proteins to keep its pro-apoptotic activity in check?Overexpression of peptidyl-prolyl isomerase Pin1 attenuates hepatocytes apoptosis and secondary necrosis following carbon tetrachloride-induced acute liver injury in mice.An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways.Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils.Bax exists in a dynamic equilibrium between the cytosol and mitochondria to control apoptotic priming Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity Combination of endogenous neural stem cell mobilization and lithium chloride treatment for hydrocephalus following intraventricular hemorrhage.Protein Translation and Signaling in Human Eosinophils Transforming Growth Factor-β1 Antagonizes Interleukin-5 Pro-Survival Signaling by Activating Calpain-1 in Primary Human Eosinophils.Phosphate Transfer in Activated Protein Complexes Reveals Interaction Sites.Parkin promotes proteasomal degradation of misregulated BAX.

P2860

Q24298758-45C0B8BD-D6D9-4E05-92F0-D09848695F3C Q27024695-97D81869-3BBE-4476-994A-AE7F012D1F7B Q27319928-2C9661C8-01EA-42EF-BC90-870209ED6F93 Q28276574-D403F538-6DB6-481D-AC7D-2A57824E1305 Q28300914-3E5507CA-A337-44A7-9E38-C75CBDE6ED69 Q28572621-ABDB624C-3C40-45CB-9F59-7C8096FC8E2A Q33728138-A722F725-5489-4495-84D4-6083C1B2122A Q33793988-200C1B2C-7FA6-46B2-9C5F-3F559E4065B0 Q34125273-2EE7E75E-97F5-4CCD-96F6-1D45E0BDAD1D Q34541535-AE4839D1-5A18-4F59-A0A8-F161CBA87851 Q34719741-7F8746C4-2C37-4134-83E6-F525ADD45B2D Q34722912-E585D1CC-EBAF-44CF-A7D1-1EC51AD69025 Q35109566-3AC7F547-A69A-4D6A-AB11-CCA35CCA8AE1 Q35659007-4B7FC57D-FACD-4248-B34A-72A8C7A96677 Q35987570-F26E24CB-9D22-43C3-A134-EF22A0D986A4 Q36078699-D0F3425A-0FA5-4192-B153-8327D9F52054 Q37048463-946BBD1B-347E-405E-B53A-4675EC96671A Q37191036-B03D64D1-2148-4C0B-9650-88ED54A0A6E5 Q37433244-85E1E28F-7E4D-4EBC-B3DC-6ABBF70FAB8E Q37828794-F9DF3A37-D468-4BCD-B1EA-A12500334793 Q37891181-938FBF40-BA85-4A07-A696-F13613FDFF2C Q38130013-896BEE43-997F-4C5A-A275-5E4A013CC09D Q38194031-BA0A5743-4D0B-48A1-81EC-4FDF3DBCBABE Q38256352-3FF1A384-BC30-4745-B528-DA0DD0F61738 Q38309222-F1CA5C7C-E04F-49ED-B534-372BE9A6A455 Q38939954-797F4DE9-FA1A-4A80-A981-032D2C7D4DF5 Q39082906-495237F5-A4BD-4A32-B47C-228C1472C179 Q39205142-03591D39-5EFB-4212-8AF0-B3A29D5CDEEC Q39406288-1BA1C3C7-93E7-45DB-B462-C91507456108 Q39423783-F1B55F98-1119-4CD6-AC45-14C46D267602 Q39593727-92EE2E78-6558-4E34-9B49-530519BACB30 Q40363493-B1348E1A-2080-412D-BA73-15A210EF6B9D Q40650749-E67E9D75-EE07-49C6-BFF6-B2EA32D3B735 Q41263641-452D32A3-3E1B-46B7-85E9-5A2E3CF9E8ED Q41844317-9D97A809-C61E-4CEF-B988-7C63778AA815 Q42053359-3EBA551A-6CD8-4ED7-AAEB-3AAF69F0E63C Q42362534-760CF742-1494-4586-913F-E68F8E106790 Q42908624-64977556-9CE6-4CAF-8834-3A76C7549FA5 Q47860185-B6503BA5-B7BB-4AA9-B694-7C576FBE05D0 Q48006875-53378C3A-AD36-47D8-8BDC-445B21D61D32

P2860

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

http://www.wikidata.org/entity/Q33762811

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@ast

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@en

type

label

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@ast

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@en

prefLabel

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@ast

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@en

P1433

Q33762811-D00D019C-AD29-484C-9431-D7B5506D3D8A

P1476

Q33762811-911700C1-10A7-4CD2-B216-BFAC4847DB78

P2093

Q33762811-92B685E2-A7AD-4A9D-9CD4-21DEA0E41306

Q33762811-B9579D3A-4341-41E2-A943-9DA3096970BD

Q33762811-FD865180-2925-4E9D-B048-5E9275B5073B

Q33762811-FF61C955-A45C-4615-AD60-1E8997246325

P2860

Q33762811-0B1A77B3-A937-4BA2-8DB6-1BE776BAD67C

Q33762811-0D4269D0-50D0-4EBC-A88A-1EE8CB9D6782

Q33762811-0EC0091C-68FF-4874-AEAD-1D0CED8C6193

Q33762811-11692A9D-8DFD-426E-A12F-CB2424163CE0

Q33762811-147E807C-2F30-439E-93FE-B5DF573C231D

Q33762811-1C665708-AB20-465B-9498-0ABE6ED6DF73

Q33762811-26B8B43A-8A1B-4DE2-BFCF-F190876448A5

Q33762811-29E7EFAD-C803-43EC-8862-B310129A24CF

Q33762811-2D57B7C3-9DA5-42F8-98BA-1275B719617C

Q33762811-37736DF9-8905-4FB9-A27A-D5A0BEECD678

P2888

Q33762811-CD48841F-EE12-43A0-B9E9-F8602A8AE9BF

P304

Q33762811-73FABDD4-4D5D-43BA-997E-D116D00395C5

P31

Q33762811-58127FAC-ECEB-4F60-B221-B2EAC80A04C4

P356

Q33762811-B2C36DBE-5454-48FB-A46C-12AA1D84CF5A

P407

Q33762811-46620E66-5400-4874-B8EB-293FAFE9403E

P433

Q33762811-B9C7A8FD-9112-4594-A089-624B98F81711

P478

Q33762811-67A881BC-FA9F-4AC7-9DD6-16A6E53BF647

P50

Q33762811-20E4CDA8-2EA9-481D-B212-83F8A575E449

P577

Q33762811-7C8BF5BE-33B0-4903-9BF7-B9176420B9AE

P5875

Q33762811-F77BCE5B-356E-4070-9680-D74710BA3E87

P6179

Q33762811-2ECB928E-15E5-4375-A0BF-57D5D4AAE258

P698

Q33762811-82E8402A-5B25-4A7F-B983-4D2CA83E9E1E

P932

Q33762811-FF23574C-969C-4975-998A-2B1CDC45123A

P356

P1433

Nature Immunology

P1476

The peptidyl-prolyl isomerase ...... by suppressing Bax activation.

@en

P2093

Anna Schinzel

http://www.w3.org/2001/XMLSchema#string

Christoph Borner

http://www.w3.org/2001/XMLSchema#string

James S Malter

http://www.w3.org/2001/XMLSchema#string

Zhong-Jian Shen

http://www.w3.org/2001/XMLSchema#string

P2860

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

Humanin peptide suppresses apoptosis by interfering with Bax activation

Clusterin inhibits apoptosis by interacting with activated Bax

Structure of Bax: coregulation of dimer formation and intracellular localization

Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge

Pinning down proline-directed phosphorylation signaling

Phosphorylation-specific prolyl isomerization: is there an underlying theme?

Fatal liaisons of p53 with Bax and Bak

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery

P2888

P304

257-265

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NI.1697

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

Stephane Esnault

P577

2009-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23964653

http://www.w3.org/2001/XMLSchema#string

P6179

1052299745

http://www.w3.org/2001/XMLSchema#string

P698

19182807

http://www.w3.org/2001/XMLSchema#string

P932

2847832

http://www.w3.org/2001/XMLSchema#string