Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN. - Wikidata - awgldk - TriplyDB

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

http://www.wikidata.org/entity/Q33762935

about

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase.c-Src complex Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!Diabetes induces changes in ILK, PINCH and components of related pathways in the spinal cord of rats.Trastuzumab induced in vivo tissue remodelling associated in vitro with inhibition of the active forms of AKT and PTEN and RhoB induction in an ovarian carcinoma model.Nephrin phosphorylation regulates podocyte adhesion through the PINCH-1-ILK-α-parvin complex Modulation of microvascular smooth muscle adhesion and mechanotransduction by integrin-linked kinase.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.ILK mediates the effects of strain on intestinal epithelial wound closure Modulation of integrin-linked kinase (ILK) expression in human oesophageal squamous cell carcinoma cell lines by the EGF and TGFbeta1 growth factors.The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation.PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue.mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen.Secreted protein acidic and rich in cysteine (SPARC) inhibits integrin-mediated adhesion and growth factor-dependent survival signaling in ovarian cancer.Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.Epigenetic manipulation of gene expression: a toolkit for cell biologists The parvins.Actopaxin (α-parvin) phosphorylation is required for matrix degradation and cancer cell invasion PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells.Particularly interesting cysteine- and histidine-rich protein in cardiac development and remodeling.Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue.Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis.Integrin-linked kinase activity modulates the pro-metastatic behavior of ovarian cancer cells.Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans.Critical role of integrin-linked kinase in granule cell precursor proliferation and cerebellar development.There's something about ILK.Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption.Integrin-linked kinase: not so 'pseudo' after all.ILK: a pseudokinase with a unique function in the integrin-actin linkage.Integrin-linked kinase in gastric cancer cell attachment, invasion and tumor growth.Parathyroid hormone-related protein promotes epithelial-mesenchymal transition An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading.Expression of integrin-linked kinase in the murine lens is consistent with its role in epithelial-mesenchymal transition of lens epithelial cells in vitro.

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P2860

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

http://www.wikidata.org/entity/Q33762935

description

2003 nî lūn-bûn

@nan

2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

@wuu

name

Integration of cell attachment ...... and the tumor suppressor PTEN.

@ast

Integration of cell attachment ...... and the tumor suppressor PTEN.

@en

type

label

Integration of cell attachment ...... and the tumor suppressor PTEN.

@ast

Integration of cell attachment ...... and the tumor suppressor PTEN.

@en

prefLabel

Integration of cell attachment ...... and the tumor suppressor PTEN.

@ast

Integration of cell attachment ...... and the tumor suppressor PTEN.

@en

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P356

MBC.E03-05-0308

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Molecular Biology of the Cell

P1476

Integration of cell attachment ...... and the tumor suppressor PTEN.

@en

P2093

Armelle Troussard

http://www.w3.org/2001/XMLSchema#string

Chuanyue Wu

http://www.w3.org/2001/XMLSchema#string

Julia Mills

http://www.w3.org/2001/XMLSchema#string

Sarah Attwell

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Shoukat Dedhar

http://www.w3.org/2001/XMLSchema#string

P2860

Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

Cell-substrate interactions and signaling through ILK

Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

P304

4813-4825

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scholarly article

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10.1091/MBC.E03-05-0308

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14

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12960424

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P932

284786

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