Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.
about
DNA damage control: regulation and functions of checkpoint kinase 1Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1.Analysis of global DNA methylation changes in primary human fibroblasts in the early phase following X-ray irradiation.Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1.PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins.Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process.Early S-phase cell hypersensitivity to heat stress.ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.CPT11 prevents virus replication in JCI cells persistently infected with JC polyomavirus.The G2 checkpoint-a node-based molecular switch.The CDK-PLK1 axis targets the DNA damage checkpoint sensor protein RAD9 to promote cell proliferation and tolerance to genotoxic stress.CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis.The cancer genome: from structure to function.Expression feels two pulses
P2860
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P2860
Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@ast
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@en
type
label
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@ast
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@en
prefLabel
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@ast
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@en
P2093
P2860
P356
P1476
Homeostatic control of polo-li ...... heckpoint fidelity and timing.
@en
P2093
Ashok R Venkitaraman
Hongqing Liang
Philippe Collin
Siddharth De
P2860
P2888
P356
10.1038/NCOMMS5048
P407
P577
2014-06-04T00:00:00Z
P5875
P6179
1030180233