Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance. - Wikidata - awgldk - TriplyDB

Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.

Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.

http://www.wikidata.org/entity/Q33766973

about

Cancer stem cells (CSCs), cervical CSCs and targeted therapies Links between cancer stem cells and epithelial-mesenchymal transition Targeting the Y/CCAAT box in cancer: YB-1 (YBX1) or NF-Y?Surmounting chemoresistance by targeting the Y-box binding protein-1 YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation.Y-box protein-1/p18 fragment identifies malignancies in patients with chronic liver disease.Screening of peptides bound to breast cancer stem cell specific surface marker CD44 by phage display.Characteristic genes in luminal subtype breast tumors with CD44+CD24-/low gene expression signature.Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells.The Met oncogene and basal-like breast cancer: another culprit to watch out for?Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy.Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)A novel Gemini vitamin D analog represses the expression of a stem cell marker CD44 in breast cancer Anoikis mediators in oral squamous cell carcinoma.Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.High expression of Y-box-binding protein 1 is associated with local recurrence and predicts poor outcome in patients with colorectal cancer Links between the oncoprotein YB-1 and small non-coding RNAs in breast cancer.YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer.Survivin is a novel target of CD44-promoted breast tumor invasion Prognostic role of YB-1 expression in breast cancer: a meta-analysis Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.miR-382 inhibits osteosarcoma metastasis and relapse by targeting Y box-binding protein 1.YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention Expression of Y-box-binding protein YB-1 allows stratification into long- and short-term survivors of head and neck cancer patients Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer.Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells.Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity.Cancer stem cells and chemoresistance: The smartest survives the raid The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors.Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression.YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress.Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.Y-box binding protein-1 promotes hepatocellular carcinoma-initiating cell progression and tumorigenesis via Wnt/β-catenin pathway.

P2860

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P2860

Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance.

http://www.wikidata.org/entity/Q33766973

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

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Y-box binding protein-1 induce ...... e growth, and drug resistance.

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Y-box binding protein-1 induce ...... e growth, and drug resistance.

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0008-5472.CAN-09-3155

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Cancer Research

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Y-box binding protein-1 induce ...... e growth, and drug resistance.

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P2093

Abbas Fotovati

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Afshin Raouf

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Alastair H Davies

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Anna L Stratford

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Arezoo Astanehe

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Connie J Eaves

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Hans-Dieter Royer

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Isabelle M Berquin

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Jennifer H Law

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Jing Wang

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P2860

Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells

The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

Identification and characterization of ovarian cancer-initiating cells from primary human tumors

The epithelial-mesenchymal transition generates cells with properties of stem cells

Prospective identification of tumorigenic breast cancer cells

Invasive growth: a MET-driven genetic programme for cancer and stem cells

Beyond tumorigenesis: cancer stem cells in metastasis

Generation of a prostate from a single adult stem cell

Purification and unique properties of mammary epithelial stem cells

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

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2840-2851

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10.1158/0008-5472.CAN-09-3155

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7

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70

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2010-03-23T00:00:00Z

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20332234

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2848879

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