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Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein familyThe Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In VivoMultimer Formation Explains Allelic Suppression of PRDM9 Recombination HotspotsPRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration.PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination.Zinc Finger Domain of the PRDM9 Gene on Chromosome 1 Exhibits High Diversity in Ruminants but Its Paralog PRDM7 Contains Multiple Disruptive MutationsAffinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usageRuminant-specific multiple duplication events of PRDM9 before speciation.The evolutionary turnover of recombination hot spots contributes to speciation in miceRe-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice.Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain.In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites.Unraveling recombination rate evolution using ancestral recombination mapsThe Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data.The consequences of sequence erosion in the evolution of recombination hotspots.The PRDM9 KRAB domain is required for meiosis and involved in protein interactions.Construction of PRDM9 allele-specific recombination maps in cattle using large-scale pedigree analysis and genome-wide single sperm genomics.The Red Queen model of recombination hot-spot evolution: a theoretical investigation.Evidence of positive selection and concerted evolution in the rapidly evolving PRDM9 zinc finger domain in goats and sheep.Evolutionary dynamics of meiotic recombination hotspots regulator PRDM9 in bovids.Recombination rate variation in mice from an isolated island.PRDM9 and Its Role in Genetic Recombination.Genetics: Asymmetric breaks in DNA cause sterility.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Prdm9 polymorphism unveils mouse evolutionary tracks.
@ast
Prdm9 polymorphism unveils mouse evolutionary tracks.
@en
type
label
Prdm9 polymorphism unveils mouse evolutionary tracks.
@ast
Prdm9 polymorphism unveils mouse evolutionary tracks.
@en
prefLabel
Prdm9 polymorphism unveils mouse evolutionary tracks.
@ast
Prdm9 polymorphism unveils mouse evolutionary tracks.
@en
P2093
P2860
P356
P1433
P1476
Prdm9 polymorphism unveils mouse evolutionary tracks.
@en
P2093
Hiromitsu Kono
Hitoshi Suzuki
Kazuo Moriwaki
Kunihiro Ohta
Kuniya Abe
Masaru Tamura
Toshihiko Shiroishi
P2860
P304
P356
10.1093/DNARES/DST059
P50
P577
2014-01-20T00:00:00Z