The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
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Advances in sarcoma diagnostics and treatmentAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerA histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreadingMolecular basis for oncohistone H3 recognition by SETD2 methyltransferaseEssential role for centromeric factors following p53 loss and oncogenic transformationNutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.Marked for death: targeting epigenetic changes in cancer.Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy.Oncogenic Mechanisms of Histone H3 Mutations.The Histone Variant H3.3 in Transcriptional Regulation and Human Disease.SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation.Shaping the cellular landscape with Set2/SETD2 methylation.A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells.Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application.Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.Fibrin glue mediated delivery of bone anabolic reagents to enhance healing of tendon to bone.Histone 3 lysine 36 to methionine mutations stably interact with and sequester SDG8 in Arabidopsis thaliana.Oncohistones: drivers of pediatric cancers.A Metabolic Function for Phospholipid and Histone Methylation.Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation.Epigenetics: Histone mutations reprogramme chondroblastoma.Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.The Making of Leukemia.Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.Kinetic Analysis of the Inhibition of the NSD1, NSD2 and SETD2 Protein Lysine Methyltransferases by a K36M Oncohistone PeptideRoles of H3K36-specific histone methyltransferases in transcription: antagonizing silencing and safeguarding transcription fidelityCancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interactionInhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastomaH3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells
P2860
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P2860
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@ast
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@en
type
label
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@ast
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@en
prefLabel
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@ast
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@en
P2093
P2860
P356
P1433
P1476
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
@en
P2093
Andre J van Wijnen
Andre M Oliveira
Brian P Rubin
Haiyun Gan
Honglian Zhang
Jennifer J Westendorf
Jeong-Heon Lee
Jianji Chen
P2860
P304
P356
10.1126/SCIENCE.AAE0065
P407
P577
2016-05-26T00:00:00Z