The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas - Wikidata - awgldk - TriplyDB

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

http://www.wikidata.org/entity/Q33768720

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Advances in sarcoma diagnostics and treatment Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase Essential role for centromeric factors following p53 loss and oncogenic transformation Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.Marked for death: targeting epigenetic changes in cancer.Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy.Oncogenic Mechanisms of Histone H3 Mutations.The Histone Variant H3.3 in Transcriptional Regulation and Human Disease.SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation.Shaping the cellular landscape with Set2/SETD2 methylation.A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo.Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells.Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application.Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.Fibrin glue mediated delivery of bone anabolic reagents to enhance healing of tendon to bone.Histone 3 lysine 36 to methionine mutations stably interact with and sequester SDG8 in Arabidopsis thaliana.Oncohistones: drivers of pediatric cancers.A Metabolic Function for Phospholipid and Histone Methylation.Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation.Epigenetics: Histone mutations reprogramme chondroblastoma.Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.The Making of Leukemia.Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.Kinetic Analysis of the Inhibition of the NSD1, NSD2 and SETD2 Protein Lysine Methyltransferases by a K36M Oncohistone Peptide Roles of H3K36-specific histone methyltransferases in transcription: antagonizing silencing and safeguarding transcription fidelity Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

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The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

http://www.wikidata.org/entity/Q33768720

description

2016 nî lūn-bûn

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2016 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2016 թվականի մայիսին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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type

label

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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prefLabel

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

@ast

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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SCIENCE.AAE0065

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The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

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Andre J van Wijnen

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Andre M Oliveira

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Brian P Rubin

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Dong Fang

http://www.w3.org/2001/XMLSchema#string

Haiyun Gan

http://www.w3.org/2001/XMLSchema#string

Honglian Zhang

http://www.w3.org/2001/XMLSchema#string

Hui Zhou

http://www.w3.org/2001/XMLSchema#string

Jennifer J Westendorf

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Jeong-Heon Lee

http://www.w3.org/2001/XMLSchema#string

Jianji Chen

http://www.w3.org/2001/XMLSchema#string

P2860

H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

Histone variants--ancient wrap artists of the epigenome

Distinct factors control histone variant H3.3 localization at specific genomic regions

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.

CRISPR/Cas9 for genome editing: progress, implications and challenges.

H3K36 methylation antagonizes PRC2-mediated H3K27 methylation

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1344-1348

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scholarly article

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10.1126/SCIENCE.AAE0065

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6291

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352

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Elizabeth W Bradley

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2016-05-26T00:00:00Z

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27229140

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5460624

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