Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM
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The murine homolog (Mph) of human herpesvirus entry protein B (HveB) mediates entry of pseudorabies virus but not herpes simplex virus types 1 and 2Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM).The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein DRoles for endocytosis and low pH in herpes simplex virus entry into HeLa and Chinese hamster ovary cellsPrevention of genital herpes in a guinea pig model using a glycoprotein D-specific single chain antibody as a microbicideStructural basis for the antibody neutralization ofHerpes simplex virusEntry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveCInhibition of herpes simplex virus gD and lymphotoxin-alpha binding to HveA by peptide antagonists.Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infectionAnti-glycoprotein H antibody impairs the pathogenicity of varicella-zoster virus in skin xenografts in the SCID mouse model.Three-dimensional structure of herpes simplex virus type 1 glycoprotein D at 2.4-nanometer resolutionHerpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein 1 or herpesvirus entry mediator, two structurally unrelated mediators of virus entry.Functional region IV of glycoprotein D from herpes simplex virus modulates glycoprotein binding to the herpesvirus entry mediatorExamination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonanceStructural and antigenic analysis of a truncated form of the herpes simplex virus glycoprotein gH-gL complex.Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization.Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infectionThe first immunoglobulin-like domain of HveC is sufficient to bind herpes simplex virus gD with full affinity, while the third domain is involved in oligomerization of HveC.The major neutralizing antigenic site on herpes simplex virus glycoprotein D overlaps a receptor-binding domain.Localization of a binding site for herpes simplex virus glycoprotein D on herpesvirus entry mediator C by using antireceptor monoclonal antibodies.Localization of the gD-binding region of the human herpes simplex virus receptor, HveAGlobal sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging.Repertoire of epitopes recognized by serum IgG from humans vaccinated with herpes simplex virus 2 glycoprotein DThe soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entryHSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis.Soluble V domain of Nectin-1/HveC enables entry of herpes simplex virus type 1 (HSV-1) into HSV-resistant cells by binding to viral glycoprotein DAntibody-induced conformational changes in herpes simplex virus glycoprotein gD reveal new targets for virus neutralization.Herpes virus fusion and entry: a story with many characters.Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.Epitope mapping of herpes simplex virus type 2 gH/gL defines distinct antigenic sites, including some associated with biological function.Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEMDissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humansThe domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1Effects of herpes simplex virus on structure and function of nectin-1/HveC.Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimerasStructure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface.Cellular and viral requirements for rapid endocytic entry of herpes simplex virus.Function of herpes simplex virus type 1 gD mutants with different receptor-binding affinities in virus entry and fusionLow-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity.Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells.
P2860
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P2860
Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@ast
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@en
type
label
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@ast
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@en
prefLabel
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@ast
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@en
P2093
P2860
P1433
P1476
Monoclonal antibodies to disti ...... in D block HSV binding to HVEM
@en
P2093
A V Nicola
C Krummenacher
J C Whitbeck
M Ponce de Leon
R I Montgomery
R J Eisenberg
P2860
P304
P50
P577
1998-05-01T00:00:00Z