The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
about
Comparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator?The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegansABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus ProductionPackaging of fat: an evolving model of lipid droplet assembly and expansionMouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modificationMechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidolInterleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysisSkeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulationAdiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1Lipid Droplets in Health and Disease.Inhibition of lipolysis in the novel transgenic quail model overexpressing G0/G1 switch gene 2 in the adipose tissue during feed restriction.Lipid droplets: size matters.The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively.CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance.Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes.Clinical and genetic characterization of Chanarin-Dorfman syndrome patients: first report of large deletions in the ABHD5 gene.DGK1-encoded diacylglycerol kinase activity is required for phospholipid synthesis during growth resumption from stationary phase in Saccharomyces cerevisiaeLipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase.Not just fat: the structure and function of the lipid droplet.CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localizationIdentification of diverse lipid droplet targeting motifs in the PNPLA family of triglyceride lipasesMammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingHuman frame shift mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB-hydrolase-containing 5 (ABHD5)Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity.SteatoNet: the first integrated human metabolic model with multi-layered regulation to investigate liver-associated pathologies.Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoringGermline ablation of VGF increases lipolysis in white adipose tissue.Trans-Golgi proteins participate in the control of lipid droplet and chylomicron formationBiochemistry and pathophysiology of intravascular and intracellular lipolysis.Insulin signalling mechanisms for triacylglycerol storage.Function of Lipid Storage Droplet 1 (Lsd1) in Wing Development of Drosophila melanogaster.Lipid droplets and cellular lipid metabolism.Targeting Fat: Mechanisms of Protein Localization to Lipid DropletsFat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes.Recent insights into the structure and function of comparative gene identification-58.Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.Chemical modulation of glycerolipid signaling and metabolic pathways.Lipid droplet dynamics in budding yeast.
P2860
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P2860
The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The N-terminal region of compa ...... f adipose triglyceride lipase.
@ast
The N-terminal region of compa ...... f adipose triglyceride lipase.
@en
type
label
The N-terminal region of compa ...... f adipose triglyceride lipase.
@ast
The N-terminal region of compa ...... f adipose triglyceride lipase.
@en
prefLabel
The N-terminal region of compa ...... f adipose triglyceride lipase.
@ast
The N-terminal region of compa ...... f adipose triglyceride lipase.
@en
P2093
P2860
P50
P356
P1476
The N-terminal region of compa ...... f adipose triglyceride lipase.
@en
P2093
Astrid Gruber
Christina Eder
Irina Cornaciu
Manju Kumari
Margret Poeschl
P2860
P304
12289-12298
P356
10.1074/JBC.M109.064469
P407
P50
P577
2010-02-17T00:00:00Z