Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.
about
Fragment screening and HIV therapeuticsDetecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment ScreeningSubstrate Deconstruction and the Nonadditivity of Enzyme RecognitionIncreasing Chemical Space Coverage by Combining Empirical and Computational Fragment ScreensMetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous MetabolitesBiosensor-based small molecule fragment screening with biolayer interferometry.Emerging role of surface plasmon resonance in fragment-based drug discovery.A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline.Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.Fragment-based approaches to anti-HIV drug discovery: state of the art and future opportunities.Critical Evaluation of Native Electrospray Ionization Mass Spectrometry for Fragment-Based Screening.Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures.The role of strong electrostatic interactions at the dimer interface of human glutathione synthetase.Thermodynamic Profiling of Carbonic Anhydrase Inhibitors
P2860
Q26826945-E2DE11EF-53FE-466B-932B-0C8BAF659B49Q27675974-20DA2C12-755F-4DE1-ADD7-03250C0A2B25Q27683622-B9A98ED4-E3AB-4DF1-BD73-E10A1C1C9F01Q27683679-30455E7C-BB21-4B18-9503-6C7F9D2DC4ABQ28597594-4E37FCA6-88F4-46B1-8247-97D229C2981FQ33928781-93E94E73-8D0A-4A13-81BE-433495E11D52Q34049517-223CB187-B8B5-43E6-BE43-4AFD1FBA8675Q35065764-094E79B0-95D9-462A-956D-DC9D80DBB793Q35650700-A040218B-3D0F-4D80-AC4F-6ED6537FCE31Q38587368-9EAF6241-8E17-4BCC-A163-045CB97A7666Q38724133-7418403F-5069-475C-BABC-D2A6FF67B890Q41959283-2768DF1D-03E8-4573-8A5F-F3D892A0AAA4Q42921549-E89B00B4-5257-4A5A-9592-2B6EF6B943B3Q58293116-D60C90A6-3438-4B0B-BC1A-AF207ADF6E5D
P2860
Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Identification of a novel scaf ...... by fragment library screening.
@ast
Identification of a novel scaf ...... by fragment library screening.
@en
type
label
Identification of a novel scaf ...... by fragment library screening.
@ast
Identification of a novel scaf ...... by fragment library screening.
@en
prefLabel
Identification of a novel scaf ...... by fragment library screening.
@ast
Identification of a novel scaf ...... by fragment library screening.
@en
P2093
P356
P1476
Identification of a novel scaf ...... by fragment library screening
@en
P2093
Christian Seeger
Iwan J P de Esch
Malin Elinder
Matthis Geitmann
U Helena Danielson
P304
P356
10.1021/JM1010513
P407
P50
P577
2011-01-05T00:00:00Z