Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).
about
Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonucleaseWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityHuman exonuclease I is required for 5' and 3' mismatch repairWRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkMultiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeThe 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instabilityComparative genomics and molecular dynamics of DNA repeats in eukaryotesHomologous Recombination and Its Role in CarcinogenesisDestabilization of tetranucleotide repeats in Haemophilus influenzae mutants lacking RnaseHI or the Klenow domain of PolIA tandem repeats database for bacterial genomes: application to the genotyping of Yersinia pestis and Bacillus anthracisAdvances in mechanisms of genetic instability related to hereditary neurological diseases.The balancing act of DNA repeat expansionsThe multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domainsAnalysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae.Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiaeAccumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.Reconstituted Okazaki fragment processing indicates two pathways of primer removal.Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway.Evidence for a role of FEN1 in maintaining mitochondrial DNA integrityInteractions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeastSensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase delta in Saccharomyces cerevisiae.In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zetaMutational landscape of yeast mutator strainsAllelic variation of a Beauveria bassiana (Ascomycota: Hypocreales) minisatellite is independent of host range and geographic origin.Mutational spectrum analysis of RNase H(35) deficient Saccharomyces cerevisiae using fluorescence-based directed termination PCR.Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.Efficient repair of large DNA loops in Saccharomyces cerevisiaeThe 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae.A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism.Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavageBacteriophage T4 rnh (RNase H) null mutations: effects on spontaneous mutation and epistatic interaction with rII mutations.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionOkazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.Ser/Thr-rich domains are associated with genetic variation and morphogenesis in Saccharomyces cerevisiae.Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loaderA mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequencesGenetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.
P2860
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P2860
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@ast
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@en
type
label
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@ast
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@en
prefLabel
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@ast
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@en
P2093
P2860
P356
P1476
Destabilization of yeast micro ...... DNA polymerase delta (pol3-t).
@en
P2093
D A Gordenin
L Stefanovic
M A Resnick
R J Kokoska
P2860
P304
P356
10.1128/MCB.18.5.2779
P407
P577
1998-05-01T00:00:00Z