Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress.
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The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in NeurodegenerationGlycoprotein Quality Control and Endoplasmic Reticulum StressNeurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrPReview: Modulating the unfolded protein response to prevent neurodegeneration and enhance memoryExpression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunctionAltered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob diseaseEndoplasmic reticulum stress and inflammation in the central nervous systemAltered Prion protein expression pattern in CSF as a biomarker for Creutzfeldt-Jakob disease.Protein disulfide isomerase regulates endoplasmic reticulum stress and the apoptotic process during prion infection and PrP mutant-induced cytotoxicity.Clinical and pathologic features of H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphismProtein Disulfide Isomerase Superfamily in Disease and the Regulation of ApoptosisProteomics analysis of amyloid and nonamyloid prion disease phenotypes reveals both common and divergent mechanisms of neuropathogenesisHIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytesPrion infections and anti-PrP antibodies trigger converging neurotoxic pathways.Differential molecular chaperone response associated with various mouse adapted scrapie strains.Dysfunction of microtubule-associated proteins of MAP2/tau family in Prion disease.Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders.Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology.Synaptic dysfunction in prion diseases: a trafficking problem?The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress.Possible role for Ca2+ in the pathophysiology of the prion protein?Protein secretion and the endoplasmic reticulum.Astrocyte signaling and neurodegeneration: new insights into CNS disorders.Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integrationThe role of protein conformational switches in pharmacology: its implications in metabolic reprogramming and protein evolution.Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.Unfolded Protein Response Pathways in Neurodegenerative Diseases.Abnormal calcium homeostasis and protein folding stress at the ER: A common factor in familial and infectious prion disorders.ER stress and the unfolded protein response in neurodegeneration.The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein.Prion aggregates transfer through tunneling nanotubes in endocytic vesiclesThe role of STIM1 in the Cr(vi)-induced [Ca(2+)]i increase and cell injury in L-02 hepatocytes.The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic SignificanceER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?Activation of autophagic programmed cell death and innate immune gene expression reveals immuno-competence of integumental epithelium in Bombyx mori infected by a dipteran parasitoid.ERp57 as a novel cellular factor controlling prion protein biosynthesis: Therapeutic potential of protein disulfide isomerasesOverexpression of quality control proteins reduces prion conversion in prion-infected cellsCrosstalk between Endoplasmic Reticulum Stress and Protein Misfolding in Neurodegenerative Diseases
P2860
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P2860
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@ast
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@en
type
label
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@ast
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@en
prefLabel
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@ast
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@en
P2093
P2860
P1433
P1476
Prion protein misfolding affec ...... endoplasmic reticulum stress.
@en
P2093
Andrés Stutzin
Claudio Hetz
Claudio Soto
Karen Castillo
Mauricio Torres
P2860
P304
P356
10.1371/JOURNAL.PONE.0015658
P407
P577
2010-12-29T00:00:00Z