Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry.
about
NNAlign: a web-based prediction method allowing non-expert end-user discovery of sequence motifs in quantitative peptide dataHuman DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.Selection of proteins with desired properties from natural proteome libraries using mRNA display.Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen.Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites.RC1339/APRc from Rickettsia conorii is a novel aspartic protease with properties of retropepsin-like enzymesFunctional protease profiling for diagnosis of malignant disease.Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide librariesBiochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities.Multiple enzyme approach for the characterization of glycan modifications on the C-terminus of the intestinal MUC2mucin.Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substratesStructural and biochemical characterization of a novel aminopeptidase from human intestine.Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterationsProteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase.Enzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanella denitrificans.Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative ProteomicsMultiplexed Protease Specificity Profiling Using Isobaric Labeling.A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity.The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis.Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14.N-glycosylation of Campylobacter jejuni surface proteins promotes bacterial fitness.Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.Proteolytic post-translational modification of proteins: proteomic tools and methodology.N- and C-terminal degradomics: new approaches to reveal biological roles for plant proteases from substrate identification.Mass spectrometry-based proteomics strategies for protease cleavage site identification.Proteomic identification of protease cleavage sites: cell-biological and biomedical applications.Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer.Unleashing the therapeutic potential of human kallikrein-related serine proteases.TAILS N-terminomic and proteomic datasets of healthy human dental pulp.Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site.The application of terminomics for the identification of protein start sites and proteoforms in bacteria.Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency.Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella.Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.Block-based characterization of protease specificity from substrate sequence profile.LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.Mass spectrometry based proteomics analyses in kallikrein-related peptidase research: implications for cancer research and therapy.Functional and structural characterization of synthetic cardosin B-derived rennet.Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
P2860
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P2860
Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Characterization of the prime ...... and tandem mass spectrometry.
@ast
Characterization of the prime ...... and tandem mass spectrometry.
@en
type
label
Characterization of the prime ...... and tandem mass spectrometry.
@ast
Characterization of the prime ...... and tandem mass spectrometry.
@en
prefLabel
Characterization of the prime ...... and tandem mass spectrometry.
@ast
Characterization of the prime ...... and tandem mass spectrometry.
@en
P2860
P50
P356
P1433
P1476
Characterization of the prime ...... s and tandem mass spectrometry
@en
P2093
Oliver Schilling
Olivier Barré
P2860
P2888
P304
P356
10.1038/NPROT.2010.178
P577
2011-01-06T00:00:00Z
P5875
P6179
1016176838