PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes

PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes

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http://www.wikidata.org/entity/Q33792380

Q33792380

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Galanin-acetylcholine interactions in rodent memory tasks and Alzheimer's disease.Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat.CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the rat.Pharmacological strategies in relieving neuropathic pain.Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.Cholecystokinin antagonists--a toxicologic perspective.Structure-based design in drug discovery--the application of a peptoid drug design strategy for the development of non-peptide neuropeptide receptor ligands.Cholecystokinin receptors mediate tolerance to the analgesic effect of TENS in arthritic rats.Ionic mechanisms underlying cholecystokinin action in rat brain.CCK in cerebral cortex and at the spinal level.Effect of CCK receptor antagonists on the antinociceptive, reinforcing and gut motility properties of morphine.Antidepressant-like effects of CCKB antagonists in mice: antagonism by naltrindole.Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain.Evaluation of a series of novel CCKB antagonists using a functional assay in the rat central nervous system Cholecystokinin as a factor in the enhanced potency of spinal morphine following carrageenin inflammation Circuitry underlying antiopioid actions of cholecystokinin within the rostral ventromedial medulla.Morphine-induced in vivo release of spinal cholecystokinin is mediated by delta-opioid receptors--effect of peripheral axotomy.Concurrent chronic administration of a CCK(B) antagonist can decrease tolerance to the ataxic effects of ethanol.Human pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist.Pharmacological characterization of morphine-induced in vivo release of cholecystokinin in rat dorsal horn: effects of ion channel blockers.Relationship between vulnerability to reinforcing effects of morphine and activity of the endogenous cholecystokinin system in Lewis and Fischer rats.

P2860

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P2860

PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexes

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http://www.wikidata.org/entity/Q33792380

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1990 nî lūn-bûn

@nan

1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

1990年の論文

@ja

1990年論文

@yue

1990年論文

@zh-hant

1990年論文

@zh-hk

1990年論文

@zh-mo

1990年論文

@zh-tw

1990年论文

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