Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
about
The bovine herpesvirus 1 immediate-early protein (bICP0) associates with histone deacetylase 1 to activate transcription.The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activityInteraction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteinsThe unique IR2 protein of equine herpesvirus 1 negatively regulates viral gene expressionComparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.Mapping the sequences that mediate interaction of the equine herpesvirus 1 immediate-early protein and human TFIIB.The UL4 protein of equine herpesvirus 1 is not essential for replication or pathogenesis and inhibits gene expression controlled by viral and heterologous promoters.The early UL3 gene of equine herpesvirus-1 encodes a tegument protein not essential for replication or virulence in the mouseThe equine herpesvirus-1 IR3 gene that lies antisense to the sole immediate-early (IE) gene is trans-activated by the IE protein, and is poorly expressed to a protein.Characterization of cis-acting elements required for autorepression of the equine herpesvirus 1 IE gene.Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication.Cytoplasmic localized infected cell protein 0 (bICP0) encoded by bovine herpesvirus 1 inhibits β interferon promoter activity and reduces IRF3 (interferon response factor 3) protein levels.Full trans-activation mediated by the immediate-early protein of equine herpesvirus 1 requires a consensus TATA box, but not its cognate binding sequence.The zinc RING finger of bovine herpesvirus 1-encoded bICP0 protein is crucial for viral replication and virulence.A negative regulatory element (base pairs -204 to -177) of the EICP0 promoter of equine herpesvirus 1 abolishes the EICP0 protein's trans-activation of its own promoter.Regulation of Innate Immune Responses by Bovine Herpesvirus 1 and Infected Cell Protein 0 (bICP0).Similar regulation of two distinct UL24 promoters by regulatory proteins of equine herpesvirus type 1 (EHV-1).Disruption of Bombyx mori nucleopolyhedrovirus ORF71 (Bm71) results in inefficient budded virus production and decreased virulence in host larvae.The alpha-TIF (VP16) homologue (ETIF) of equine herpesvirus 1 is essential for secondary envelopment and virus egress.Comparative Genomic Sequencing and Pathogenic Properties of Equine Herpesvirus 1 KyA and RacL11.
P2860
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P2860
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
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Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
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Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
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type
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Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
@ast
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
@en
prefLabel
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
@ast
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
@en
P2093
P2860
P1433
P1476
Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein
@en
P2093
D E Bowles
D J O'Callaghan
P2860
P304
P356
10.1128/JVI.74.3.1200-1208.2000
P577
2000-02-01T00:00:00Z