Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. - Wikidata - awgldk - TriplyDB

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

http://www.wikidata.org/entity/Q33795240

about

Tumor angiogenesis and lymphangiogenesis: tumor/endothelial crosstalk and cellular/microenvironmental signaling mechanisms The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism Mechanoinduction of lymph vessel expansion.A genome-wide DNA methylation study in colorectal carcinoma.Inhibition of lymphangiogenesis in vitro and in vivo by the multikinase inhibitor nintedanib.Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation.Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis.Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.Vascular endothelial growth factor A (VEGF-A) induces endothelial and cancer cell migration through direct binding to integrin {alpha}9{beta}1: identification of a specific {alpha}9{beta}1 binding site.A PKA-Csk-pp60Src signaling pathway regulates the switch between endothelial cell invasion and cell-cell adhesion during vascular sprouting.Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies.Cell Adhesion Mediated by VCAM-ITGα9 Interactions Enables Lymphatic Development Gap junction coupling is required for tumor cell migration through lymphatic endothelium Biomarkers as key contributors in treating malignant melanoma metastases.EILDV-conjugated, etoposide-loaded biodegradable polymeric micelles directing to tumor metastatic cells overexpressing α4β1 integrin Anti-tumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasis Tumor lymphangiogenesis as a potential therapeutic target.Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis Fibronectin-α4β1 interactions in hepatic cold ischemia and reperfusion injury: regulation of MMP-9 and MT1-MMP via the p38 MAPK pathway.Lactoferrin regulates an axis involving CD11b and CD49d integrins and the chemokines MIP-1α and MCP-1 in GM-CSF-treated human primary eosinophils.TSC2 modulates cell adhesion and migration via integrin-α1β1 The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.Netrin-4 activates endothelial integrin {alpha}6{beta}1.Integrins α4 and αM, collagen1A1, and matrix metalloproteinase 7 are upregulated in acute Kawasaki disease vasculopathy.Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature.Recombinant canstatin inhibits VEGF-A-induced lymphangiogenesis and metastasis in an oral squamous cell carcinoma SCC-VII animal model.Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins.Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function Genetic analyses of integrin signaling.Mechanical forces in lymphatic vascular development and disease.Lymphangiogenesis and lymphatic vessel remodelling in cancer.Vascular cell adhesion molecule-1 (VCAM-1)--an increasing insight into its role in tumorigenicity and metastasis.The novel α4B murine α4 integrin protein splicing variant inhibits α4 protein-dependent cell adhesion.Contribution of very late antigen-4 (VLA-4) integrin to cancer progression and metastasis.A longitudinal MRI study on lymph nodes histiocytosis of a xenograft cancer model.Cellular fibronectin 1 promotes VEGF-C expression, lymphangiogenesis and lymph node metastasis associated with human oral squamous cell carcinoma.

P2860

Q26830901-94C90368-102A-4136-A6EE-4E620299B5A8 Q27680703-EF66C07A-F2E9-448D-ABED-C408A42C2160 Q30505376-F2339863-D596-41CA-9207-60E694EE0AD2 Q31020320-6BBB508F-88FA-44A4-A0BB-928A2C67F9FA Q33563488-C1D1F6F2-C25C-43B1-9B0A-01BE0A551519 Q33963025-380ACCB2-F025-49F7-9D80-4E9C31A068D9 Q34326240-B309EDC2-CC2F-4A9A-91F2-0F91A65E1757 Q34472031-72CD4083-E71B-48F3-AAD8-C7B67C84E551 Q34488846-D6A58CA4-2F38-4AA1-8E08-23D7BD6AD808 Q34541791-AB1791F0-FAFF-4DB5-AAF7-6311FE772309 Q34914039-CDDA6341-7715-4696-87B1-F56B78CB2C37 Q35537280-5DD20283-B32B-406F-A718-FFBD935170F7 Q35537353-B8050CC0-3309-4441-8594-C3A131F7F308 Q35550888-BBB0CC0B-A301-4C2A-845D-9D95F997782A Q35673648-61488706-17B2-414E-A764-A9D1091647CD Q35741034-7DAB16C3-6240-465B-9A3C-70C9FB5F4142 Q35810928-76417AD3-1000-4962-8DFB-51DE3EE251B4 Q35838122-672A80E6-0602-474D-B7D5-330168F27999 Q35935011-647FEEF5-4B55-4D4E-8FC7-E8513F425003 Q35995835-0025D170-DA70-4D3C-9EEB-509D42FB596A Q36282336-A3F494E3-5CB5-455A-A577-7DF66BB7E085 Q36296976-590D825B-C294-4A05-80D4-7178B1CCF0EE Q36312486-2C6F9DB9-8420-44BE-9603-662307282AF6 Q36339264-33CAE1D1-00E3-40CA-AB3C-4B3EC5FD2B4C Q36555407-9F4D856D-2762-4E20-A742-C70D0D1F237A Q36677180-F2627F4B-7517-424E-86F0-D53FB5048910 Q36880854-C0A93D14-B859-45CE-A544-FEDE5BF38041 Q36895525-D8DA4BA4-D174-42B1-B716-D2CA11917431 Q37364878-11DD6421-F77E-4403-87A0-34CE126BAD8A Q37373141-6C8C0412-08C3-442B-A195-B1BC81803D0D Q37499263-89EA9735-2EB3-4389-916F-11669E54DF0E Q37781426-031DBD6C-634A-4AF1-B09A-94B208819A18 Q37855339-4274FF48-E80B-4519-B787-2698A22FE222 Q38105904-E677D982-53CB-4621-83BA-FE30478D73B9 Q38190359-C34BDDB2-380E-4BEE-BEE5-6F58EE84EDF9 Q38207560-43825679-F8F2-4B6D-A298-2BCE7BFF0CE4 Q38307621-3450A441-83A6-4CB3-9EE2-82AC166A6049 Q38309552-DEEED85B-281D-4F4D-85FB-D8548ED923E4 Q38697440-E8580CAE-4EC5-407C-B2DD-ADD7B87094DE Q38839716-6030FB14-BA05-4FFC-95CD-0F740416A093

P2860

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

http://www.wikidata.org/entity/Q33795240

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@ast

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@en

type

label

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@ast

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@en

prefLabel

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@ast

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.

@en

P1433

Q33795240-5585298B-322A-4B7D-B999-9A9E2A1027CE

P1476

Q33795240-F76A4E4C-F3D9-49D9-AFC8-76A6CFC20E15

P2093

Q33795240-026941D3-017D-4EC9-A2C5-A4AA92A1231A

Q33795240-0581F032-1108-4B25-BBEA-EE0E1DFBC5F8

Q33795240-335E9EEB-9B0E-4508-B3FE-4866A5E6BEC2

Q33795240-70BB3141-FC30-4B96-9E72-0E3F4A08CE19

Q33795240-731DCFB6-347D-499D-B13C-8F6E3F5C3897

Q33795240-91BF65CC-A500-4A20-BAB7-A33060068C9A

Q33795240-A9286CA7-B62F-42AB-9F9D-7049BFA0F1BD

Q33795240-B9EE5BD6-9904-4C33-BFE5-01260D170746

Q33795240-E6EA8043-5037-4D79-8873-010994ECCAB6

Q33795240-ECD35ABD-F1F8-41CC-91AE-94EDE4902160

P2860

Q33795240-0684A883-DB97-4980-B118-6AB5093D05A2

Q33795240-12524BDE-B8E3-4036-92CC-11C9783D5C8A

Q33795240-1C09136F-8DFC-4253-90F1-F2D38A047012

Q33795240-24A1EF32-88B1-4334-A618-36DF9A6EDD88

Q33795240-26BD2636-74C2-41C3-A1B7-3F0EDB28FE34

Q33795240-2B031DD0-765C-4E27-96B3-AF9EBD250699

Q33795240-4A61736A-1001-4CD7-8016-CAA853EECE59

Q33795240-56472353-193C-4E2C-8120-BBF4F249B7C4

Q33795240-565F3680-7448-4AE7-9F71-B0F63D081AE7

Q33795240-5A51AB82-A3AB-401E-BEBD-CFB50C8D64D2

P304

Q33795240-4809E1C8-0C7D-4AF2-9607-D2FC69991A05

P31

Q33795240-E4FB855C-320B-4728-AC4C-30732B3BA900

P356

Q33795240-8B4CFF7D-7BFB-4205-9116-A1686467DAF7

P407

Q33795240-4DDF1113-23A8-4A8D-955B-769BE03DB417

P433

Q33795240-5D32F12C-5DC7-4DC5-A9C8-97899A0094A7

P478

Q33795240-5888B6B7-62FA-49B8-8DDA-A3FA57B25C16

P50

Q33795240-947BF8DA-7305-4A64-B180-73C505EA4DDE

Q33795240-AD7D5C1C-792C-496C-9802-FECF364787D0

Q33795240-BB5485ED-8311-4EF4-AC36-AFB1D2B87345

P577

Q33795240-200F71BE-9C48-4E91-8D29-5B6735FA0711

P5875

Q33795240-9F14F8C9-C9EE-4817-8B00-8F76BF02DFD6

P698

Q33795240-C8AC7765-2531-4342-9E9F-5312012CA34F

P921

Q33795240-521E771C-EF38-42B4-B30B-465F46D2AA89

P932

Q33795240-14BE9A72-A2BF-47F1-ADB9-78BB1539A8E2

P356

0008-5472.CAN-09-3761

P1433

Cancer Research

P1476

Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis

@en

P2093

Andrew Lowy

http://www.w3.org/2001/XMLSchema#string

Christie J Avraamides

http://www.w3.org/2001/XMLSchema#string

David Cheresh

http://www.w3.org/2001/XMLSchema#string

Judith A Varner

http://www.w3.org/2001/XMLSchema#string

Leo Barnes

http://www.w3.org/2001/XMLSchema#string

Lesley G Ellies

http://www.w3.org/2001/XMLSchema#string

Mark Ginsberg

http://www.w3.org/2001/XMLSchema#string

Philippe Foubert

http://www.w3.org/2001/XMLSchema#string

Sarah L Blair

http://www.w3.org/2001/XMLSchema#string

Thalia Papayannopoulou

http://www.w3.org/2001/XMLSchema#string

P2860

LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

Microenvironmental regulation of metastasis

Metastasis: from dissemination to organ-specific colonization

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

Tumour lymphangiogenesis is a possible predictor of sentinel lymph node status in cutaneous melanoma: a case-control study.

Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation

P304

3042-3051

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-09-3761

http://www.w3.org/2001/XMLSchema#string

P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

70

http://www.w3.org/2001/XMLSchema#string

P50

Chloé C Féral

Michael C Schmid

Barbara Garmy-Susini

P577

2010-04-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

43133875

http://www.w3.org/2001/XMLSchema#string

P698

20388801

http://www.w3.org/2001/XMLSchema#string

P921

lymphangiogenesis

P932

2856096

http://www.w3.org/2001/XMLSchema#string