HCMV spread and cell tropism are determined by distinct virus populations.
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The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replicationBioactive Molecules Released From Cells Infected with the Human CytomegalovirusVirion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick GetawayViral Regulation of Cell Tropism in Human CytomegalovirusA Luciferase Gene Driven by an Alphaherpesviral Promoter Also Responds to Immediate Early Antigens of the Betaherpesvirus HCMV, Allowing Comparative Analyses of Different Human Herpesviruses in One Reporter Cell LineCell-free transmission of human adenovirus by passive mass transfer in cell culture simulated in a computer model.M94 is essential for the secondary envelopment of murine cytomegalovirus.Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes.The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus.A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell typesStructural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes.Mixed infection and strain diversity in congenital cytomegalovirus infectionA viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.Modeling of human cytomegalovirus maternal-fetal transmission in a novel decidual organ cultureHuman Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells.Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism.The US16 gene of human cytomegalovirus is required for efficient viral infection of endothelial and epithelial cells.Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection.Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry.Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model.The immune response to human CMVAdenovirus E1A/E1B Transformed Amniotic Fluid Cells Support Human Cytomegalovirus Replication.An endothelial cell-specific requirement for the UL133-UL138 locus of human cytomegalovirus for efficient virus maturationDifferential protein partitioning within the herpesvirus tegument and envelope underlies a complex and variable virion architecture.The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gLIn Vitro Characterization of Human Cytomegalovirus-Targeting Therapeutic Monoclonal Antibodies LJP538 and LJP539.Comparative analysis of gO isoforms reveals that strains of human cytomegalovirus differ in the ratio of gH/gL/gO and gH/gL/UL128-131 in the virion envelope.Antibody inhibition of human cytomegalovirus spread in epithelial cell culturesRepair of a Mutation Disrupting the Guinea Pig Cytomegalovirus Pentameric Complex Acquired during Fibroblast Passage Restores Pathogenesis in Immune-Suppressed Guinea Pigs and in the Context of Congenital Infection.The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains.Herpesvirus transport to the nervous system and back again.HCMV infection of human trophoblast progenitor cells of the placenta is neutralized by a human monoclonal antibody to glycoprotein B and not by antibodies to the pentamer complex.Severe Cytomegalovirus Gastritis During Natalizumab-Mediated ImmunosuppressionCytomegalovirus infection impairs immunosuppressive and antimicrobial effector functions of human multipotent mesenchymal stromal cells.Impact of Antibodies and Strain Polymorphisms on Cytomegalovirus Entry and Spread in Fibroblasts and Epithelial Cells.Loss of the Human Cytomegalovirus US16 Protein Abrogates Virus Entry into Endothelial and Epithelial Cells by Reducing the Virion Content of the Pentamer.The proteome of human cytomegalovirus virions and dense bodies is conserved across different strains.
P2860
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P2860
HCMV spread and cell tropism are determined by distinct virus populations.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
HCMV spread and cell tropism are determined by distinct virus populations.
@ast
HCMV spread and cell tropism are determined by distinct virus populations.
@en
type
label
HCMV spread and cell tropism are determined by distinct virus populations.
@ast
HCMV spread and cell tropism are determined by distinct virus populations.
@en
prefLabel
HCMV spread and cell tropism are determined by distinct virus populations.
@ast
HCMV spread and cell tropism are determined by distinct virus populations.
@en
P2093
P2860
P1433
P1476
HCMV spread and cell tropism are determined by distinct virus populations.
@en
P2093
Barbara Adler
Christian Sinzger
Hans Nitschko
Laura Scrivano
Ulrich H Koszinowski
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001256
P577
2011-01-13T00:00:00Z