Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses - Wikidata - awgldk - TriplyDB

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

http://www.wikidata.org/entity/Q33805897

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Inducing and Administering Tregs to Treat Human Disease Promises and paradoxes of regulatory T cells in inflammatory bowel disease Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.Identification of CD112R as a novel checkpoint for human T cells.Peripherally Induced Regulatory T Cells: Recruited Protectors of the Central Nervous System against Autoimmune Neuroinflammation.Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets.Human IL-6RhiTIGIT- CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile.New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016 Stroma-derived Fibrinogen-like Protein 2 Activates Cancer-associated Fibroblasts to Promote Tumor Growth in Lung Cancer TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients.Mathematical model of sarcoidosis The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226.Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.Regulatory T Cell Responses to High-Dose Methylprednisolone in Active Systemic Lupus Erythematosus HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).Inhibitory receptors as targets for cancer immunotherapy FGL2 as a Multimodality Regulator of Tumor-Mediated Immune Suppression and Therapeutic Target in Gliomas Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners Gene expression meta-analysis reveals immune response convergence on the IFNγ-STAT1-IRF1 axis and adaptive immune resistance mechanisms in lymphoma Mechanisms of immunological tolerance in central nervous system inflammatory demyelination.Coexpression of TIGIT and FCRL3 identifies Helios+ human memory regulatory T cells.TIGIT predominantly regulates the immune response via regulatory T cells.Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.AHR Function in Lymphocytes: Emerging Concepts NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs.PD-1 marks dysfunctional regulatory T cells in malignant gliomas.Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.Expression of Treg/Th17 cells as well as related cytokines in patients with inflammatory bowel disease.Singular role for T-BET+CXCR3+ regulatory T cells in protection from autoimmune diabetes.Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.Soluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signaling Direct control of regulatory T cells by keratinocytes.Elevated expression of TIGIT on CD3+CD4+ T cells correlates with disease activity in systemic lupus erythematosus.

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P2860

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

http://www.wikidata.org/entity/Q33805897

description

2014 nî lūn-bûn

@nan

2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

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name

Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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type

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Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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prefLabel

Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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J.IMMUNI.2014.02.012

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Treg cells expressing the coin ...... ry Th1 and Th17 cell responses

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P2093

Arlene H Sharpe

http://www.w3.org/2001/XMLSchema#string

Bonny Patel

http://www.w3.org/2001/XMLSchema#string

Chen Zhu

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Christophe Benoist

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David A Hafler

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Diane Mathis

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Francisco J Quintana

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Junrong Xia

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Patrick R Burkett

http://www.w3.org/2001/XMLSchema#string

Sheng Xiao

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P2860

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions

Interleukin-10-deficient mice develop chronic enterocolitis

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569-581

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scholarly article

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10.1016/J.IMMUNI.2014.02.012

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2014-04-01T00:00:00Z

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261765947

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24745333

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