Anti-leukemia activity of a bacterial toxin with natural specificity for LFA-1 on white blood cells.
about
Drugs under preclinical and clinical study for treatment of acute and chronic lymphoblastic leukemiaHIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA)Assessing the barriers to image-guided drug delivery.Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera) induces cofilin dephosphorylation and actin depolymerization during killing of malignant monocytes.Expression and targeting of lymphocyte function-associated antigen 1 (LFA-1) on white blood cells for treatment of allergic asthma.Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapyGangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysisLFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytesAggregatibacter actinomycetemcomitans QseBC is activated by catecholamines and iron and regulates genes encoding proteins associated with anaerobic respiration and metabolism.Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans.Leukotoxin kills rodent WBC by targeting leukocyte function associated antigen 1.Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway.Inhibition of LtxA toxicity by blocking cholesterol binding with peptides.Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells.Role of LFA-1 and ICAM-1 in Cancer.
P2860
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P2860
Anti-leukemia activity of a bacterial toxin with natural specificity for LFA-1 on white blood cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@ast
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@en
type
label
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@ast
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@en
prefLabel
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@ast
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@en
P2093
P2860
P1433
P1476
Anti-leukemia activity of a ba ...... or LFA-1 on white blood cells.
@en
P2093
Amy B Schwartz
Catarina E Hioe
Manpreet Kaur
Michael Tuen
Nataliya V Balashova
Scott C Kachlany
Yongyi Mei
P2860
P304
P356
10.1016/J.LEUKRES.2009.08.022
P577
2009-09-10T00:00:00Z