Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits
about
Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilizationInterdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neuronsI(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activityKv3-like potassium channels are required for sustained high-frequency firing in basal ganglia output neurons.Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior.Shal/K(v)4 channels are required for maintaining excitability during repetitive firing and normal locomotion in Drosophila.Mutations in KCND3 cause spinocerebellar ataxia type 22.Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexesKv4 channels underlie A-currents with highly variable inactivation time courses but homogeneous other gating properties in the nucleus tractus solitarii.Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes.Layer-specific modulation of neuronal excitability by 660-nm laser irradiation in mouse neocortex.Postnatal development of A-type and Kv1- and Kv2-mediated potassium channel currents in neocortical pyramidal neurons.Up-regulation of A-type potassium currents protects neurons against cerebral ischemiaEffect of tyrphostin AG879 on Kv 4.2 and Kv 4.3 potassium channels.The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.Coordinated development of voltage-gated Na+ and K+ currents regulates functional maturation of forebrain neurons derived from human induced pluripotent stem cells.The cellular building blocks of breathingRoles of specific Kv channel types in repolarization of the action potential in genetically identified subclasses of pyramidal neurons in mouse neocortexIA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus.Transient outwardly rectifying A currents are involved in the firing rate response to altered CO2 in chemosensitive locus coeruleus neurons from neonatal rats.Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway.IA channels: diverse regulatory mechanisms.Physiological roles of Kv2 channels in entorhinal cortex layer II stellate cells revealed by Guangxitoxin-1E.Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex.Somatodendritic surface expression of epitope-tagged and KChIP binding-deficient Kv4.2 channels in hippocampal neurons.Immunohistochemical localization of DPP10 in rat brain supports the existence of a Kv4/KChIP/DPPL ternary complex in neurons.A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox.De novo variants in CAMK2A and CAMK2B cause neurodevelopmental disorders.Dendritic Integration of Sensory Evidence in Perceptual Decision-Making.A-type K channels impede supralinear summation of clustered glutamatergic inputs in layer 3 neocortical pyramidal neurons
P2860
Q28590262-80104DBE-48C4-46F5-A467-520343AFB73CQ28590266-590A51AC-660C-4FA9-9C53-47014923C6D1Q28593648-695D6758-B2E2-4926-9D42-A625805C4442Q30498803-D21BA6A1-F42E-4D3F-967A-39EDE7482860Q33716160-7F392267-C167-4D45-B14D-34CA950E005BQ33802560-9EFE8F76-0C29-46D6-811E-51B6513DE5F8Q33857030-71F4526E-6D7D-4CD5-BCDC-00EED78D177FQ34236486-5B8AE1EC-253C-44EE-A976-C78C4ABAA9B9Q34421856-6BF3F34E-A649-4683-868E-4A187818A66CQ34612422-6EFC5C7F-96F0-47B6-92A3-6C2DD1EA5B64Q35043166-CAA2D771-D025-4221-8603-5A1AACF47723Q35055958-95A201B5-A5AA-42AA-9A8F-023CA9F19BFDQ35262192-16CD2448-CFF6-40D8-A8AF-987D194EF8BEQ35573896-151647E6-140E-41F9-AD08-636A9FF3F4F9Q35944812-6DC5AEA9-52CF-4EE7-A38A-23201A979E1AQ35995928-FF508DC2-FC3F-4E55-A1DE-49CF51DE0D69Q36378257-D080C11C-CEDB-4F7A-916D-3B36C00061BAQ36842162-837382D9-C220-4CB8-B207-E78E175443EAQ36933248-D770B8C8-D17F-424A-BB6B-6C2681301D71Q37041603-95AAC0DF-E753-4475-A4A8-EB5FD2534032Q37080755-F48C482F-8B4F-43C3-AE24-06FDBDD27949Q37234986-5F6BC71F-1916-4C8D-8C10-FB6A3E831062Q37242433-E1FA4017-D81A-4A9C-87E4-A2AA82703DD6Q38150820-4CDD3152-61EC-4F3F-B495-347BBCD8F60CQ42498155-BEA7D667-8576-47F8-943F-6BA842483FD1Q46987368-D0641540-F71B-4CE4-BC2B-6D41D6843A05Q48133525-C51D6711-E628-472D-A7EC-B01CCFC3B54DQ48471120-030C6BD9-DE3B-43A2-9201-8A4547779FCDQ51779695-D480D72A-9FD8-474C-BAC0-4AE24E522BF9Q52654625-AD4A2D77-425E-4D1C-A8FB-AE0D5D7272CDQ54969182-2DB2DD27-8767-4E76-8D0D-47C067B27A41Q55012878-85E561F6-1734-4D0A-B448-D4963DFC98FAQ58737948-2174407A-2A29-45DE-BCB0-0D65E83BF4CB
P2860
Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@ast
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@en
type
label
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@ast
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@en
prefLabel
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@ast
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@en
P2860
P1476
Molecular dissection of I(A) i ...... v4.3, and Kv1.4 alpha-subunits
@en
P2093
Aaron J Norris
Jeanne M Nerbonne
P2860
P304
P356
10.1523/JNEUROSCI.5890-09.2010
P407
P577
2010-04-01T00:00:00Z