Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0
about
An activation domain in the C-terminal subunit of HCF-1 is important for transactivation by VP16 and LZIP.The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genesFunctional inaccessibility of quiescent herpes simplex virus genomesOncolytic virotherapy using herpes simplex virus: how far have we come?De novo synthesis of VP16 coordinates the exit from HSV latency in vivo.ICP0 induces the accumulation of colocalizing conjugated ubiquitin.Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.Permissiveness of human cancer cells to oncolytic bovine herpesvirus 1 is mediated in part by KRAS activityHerpes simplex virus ICP0 mutants are hypersensitive to interferonHerpes simplex virus triggers and then disarms a host antiviral response.The neuronal host cell factor-binding protein Zhangfei inhibits herpes simplex virus replication.ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapyThe differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatinAn Essential Viral Transcription Activator Modulates Chromatin DynamicsDesigning Herpes Viruses as Oncolytics.The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines.Herpes simplex virus type 1 ICP0 phosphorylation mutants impair the E3 ubiquitin ligase activity of ICP0 in a cell type-dependent manner.Chromatin dynamics during lytic infection with herpes simplex virus 1.Core histones H2B and H4 are mobilized during infection with herpes simplex virus 1.Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus.Epigenetic modulation of gene expression from quiescent herpes simplex virus genomes.Cell fusion-induced activation of interferon-stimulated genes is not required for restriction of a herpes simplex virus VP16/ICP0 mutant in heterokarya formed between permissive and restrictive cells.Analysis of the functions of herpes simplex virus type 1 regulatory protein ICP0 that are critical for lytic infection and derepression of quiescent viral genomes.The UL14 tegument protein of herpes simplex virus type 1 is required for efficient nuclear transport of the alpha transinducing factor VP16 and viral capsids.The alpha-TIF (VP16) homologue (ETIF) of equine herpesvirus 1 is essential for secondary envelopment and virus egress.Human cytomegalovirus tegument protein pp71 directs long-term gene expression from quiescent herpes simplex virus genomes.Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo.Herpes simplex virus type 1 genomes are associated with ND10 nuclear substructures in quiescently infected human fibroblasts.Linker histones are mobilized during infection with herpes simplex virus type 1.Reactivation of expression from quiescent herpes simplex virus type 1 genomes in the absence of immediate-early protein ICP0.
P2860
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P2860
Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@ast
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@en
type
label
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@ast
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@en
prefLabel
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@ast
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@en
P2860
P1433
P1476
Truncation of the C-terminal a ...... ost entirely dependent on ICP0
@en
P2093
J R Smiley
K L Mossman
P2860
P304
P577
1999-12-01T00:00:00Z