A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
about
Diversity-oriented synthetic strategies applied to cancer chemical biology and drug discoverySLC transporters as therapeutic targets: emerging opportunitiesMechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amidesCreation and manipulation of common functional groups en route to a skeletally diverse chemical libraryAssembly of four diverse heterocyclic libraries enabled by Prins cyclization, Au-catalyzed enyne cycloisomerization, and automated amide synthesis.Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity.[2+2+2] Cycloadditions of siloxy alkynes with 1,2-diazines: from reaction discovery to identification of an antiglycolytic chemotype.Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876.Anticancer agents that counteract tumor glycolysis.Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism?Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection.Resistance to chemotherapy is associated with altered glucose metabolism in acute myeloid leukemia.Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux.Anticancer agents interacting with membrane glucose transporters.Clk1-regulated aerobic glycolysis is involved in glioma chemoresistance.Solute carrier transporters: potential targets for digestive system neoplasms.
P2860
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P2860
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@ast
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@en
type
label
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@ast
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@en
prefLabel
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@ast
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@en
P2093
P2860
P1476
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
@en
P2093
Jiayue Cui
Olesya A Ulanovskaya
Sergey A Kozmin
P2860
P304
P356
10.1016/J.CHEMBIOL.2010.12.015
P577
2011-02-01T00:00:00Z