Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression - Wikidata - awgldk - TriplyDB

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

http://www.wikidata.org/entity/Q33827309

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Islet biology, the CDKN2A/B locus and type 2 diabetes risk.CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection.Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cells Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans.RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1.Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch.Progress with palbociclib in breast cancer: latest evidence and clinical considerations.PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.Cyclin D1 in the Liver: Role of Noncanonical Signaling in Liver Steatosis and Hormone Regulation Diabetes mellitus--advances and challenges in human β-cell proliferation.Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.Cdk4 regulates adult neural stem cell proliferation and differentiation in response to insulin-IRS2 signals.CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation.Protein acetylation in metabolism - metabolites and cofactors.Molecular pathophysiology of hepatic glucose production.Melanocytic nevi and melanoma: unraveling a complex relationship.Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer.p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Cyclin D1, cancer progression, and opportunities in cancer treatment.Transcriptomic profiling of human embryonic stem cells upon cell cycle manipulation during pluripotent state dissolution.Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling.Overexpression of interleukin-18 protein reduces viability and induces apoptosis of tongue squamous cell carcinoma cells by activation of glycogen synthase kinase-3β signaling Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6 Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer.E2F1, a Novel Regulator of Metabolism.Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK.Cdkn2a deficiency promotes adipose tissue browning.Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.Loss of CDKN2B Promotes Fibrosis via Increased Fibroblast Differentiation Rather Than Proliferation.Insulin regulation of gluconeogenesis.CDK6 inhibits white to beige fat transition by suppressing RUNX1.Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation.

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P2860

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

http://www.wikidata.org/entity/Q33827309

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

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Helen Chim

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Ji-Hong Lim

http://www.w3.org/2001/XMLSchema#string

Joao Paulo Camporez

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John E Dominy

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Nicola Tolliday

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Pere Puigserver

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Piotr Sicinski

http://www.w3.org/2001/XMLSchema#string

Xiaoyong Yang

http://www.w3.org/2001/XMLSchema#string

Yoon Jong Choi

http://www.w3.org/2001/XMLSchema#string

Yoonjin Lee

http://www.w3.org/2001/XMLSchema#string

P2860

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

Cell cycle, CDKs and cancer: a changing paradigm

Histone-like TAFs within the PCAF histone acetylase complex

Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes.

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

P2888

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547-551

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scholarly article

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10.1038/NATURE13267

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7506

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510

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Michael J. Jurczak

Gerald I. Shulman

Francisca Vazquez

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2014-05-25T00:00:00Z

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262696507

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1029167681

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24870244

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4076706

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