Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

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http://www.wikidata.org/entity/Q33829258
Is DNA methylation the new guardian of the genome?Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma.Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model.Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention.The wayward methyl group and the cascade to cancer.The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapIndividualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients.Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: Decoy, trap and kill chRecombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models.Genetic and metabolic comparison of orthotopic and heterotopic patient-derived pancreatic-cancer xenografts to the original patient tumors.Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer.Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models.Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
P2860

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Item
http://www.wikidata.org/entity/Q33829258
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2017 nî lūn-bûn
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2017 թուականի Մարտին հրատարակուած գիտական յօդուած
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2017 թվականի մարտին հրատարակված գիտական հոդված
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2017年の論文
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2017年論文
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2017年論文
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2017年論文
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2017年論文
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2017年論文
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2017年论文
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Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@ast
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@en
type
label
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@ast
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@en
prefLabel
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@ast
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
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P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Recombinant methioninase effec ...... graft (PDOX) nude-mouse model.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932