Muscle regeneration in the prolonged absence of myostatin
about
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2Myostatin: expanding horizonsDystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures.Two novel missense mutations in the myostatin gene identified in Japanese patients with Duchenne muscular dystrophy.Systemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic miceTestosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways.The golden retriever model of Duchenne muscular dystrophy.High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo.The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny.The timing of administration of a clinically relevant dose of losartan influences the healing process after contusion induced muscle injuryContractile properties of EDL and soleus muscles of myostatin-deficient mice.The skeletal muscle satellite cell response to a single bout of resistance-type exercise is delayed with aging in men.Optimal management of sarcopenia.Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trialsRegulation of muscle mass by follistatin and activinsEndurance exercise training in myostatin null mice.Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice.Gene therapy progress and prospects: Duchenne muscular dystrophy.A novel in vitro model for studying quiescence and activation of primary isolated human myoblasts.Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosisLack of myostatin results in excessive muscle growth but impaired force generation.Approaching a new age in Duchenne muscular dystrophy treatment.Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy.Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.Mammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism.The role of myostatin and bone morphogenetic proteins in muscular disorders.The possible role of myostatin in skeletal muscle atrophy and cachexia.Myostatin Attenuation In Vivo Reduces Adiposity, but Activates AdipogenesisLong-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitorsMyostatin directly regulates skeletal muscle fibrosis.Action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling.Clinical, agricultural, and evolutionary biology of myostatin: a comparative reviewMyostatin does not regulate cardiac hypertrophy or fibrosis.Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors.Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathyIdentification of biological markers for better characterization of older subjects with physical frailty and sarcopenia.Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume.
P2860
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P2860
Muscle regeneration in the prolonged absence of myostatin
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Muscle regeneration in the prolonged absence of myostatin
@ast
Muscle regeneration in the prolonged absence of myostatin
@en
type
label
Muscle regeneration in the prolonged absence of myostatin
@ast
Muscle regeneration in the prolonged absence of myostatin
@en
prefLabel
Muscle regeneration in the prolonged absence of myostatin
@ast
Muscle regeneration in the prolonged absence of myostatin
@en
P2093
P2860
P356
P1476
Muscle regeneration in the prolonged absence of myostatin
@en
P2093
Kathryn R Wagner
Ronald E Allen
Xiaoli Chang
Xiaosong Liu
P2860
P304
P356
10.1073/PNAS.0408729102
P407
P577
2005-02-07T00:00:00Z